Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

IF HPLC CALIBRATION FAILED THEN WHAT YOU DO

6 25100

Optical Rotation*0.9477*100*200] Assay Of dextrose= ________________________________ 99.8* 200 why Factor=0.9477

Claris Lifesciences, Inven Pharmaceuticals, Levo,

1 9965

How you will select the runtime in HPLC for a drug in method development.

GVK, Lesanto Laboratories, Aurobindo,

6 14580




If compound Pka is 5 then which buffer you will select ?

GVK, Avra,

5 11329

what is the difference between BDS and ODS Columens and both are same or not

Micro Labs, Vasava Engineering Private Limited, IPQA, Intas,

2 57295

difference between HPLC & LC-MS

Lambda,

9 35895

difference between record & document ?

4 10159

in what basis wavelength will select for a compound at initial method development trials

Matrix,

4 8638




How did you conclude that when stressing a compond, all degradation products have eluted in chromatogram?

Matrix,

7 6703

how to prepare working standard in our laboratory aganist reference standard ?

Unichem, Merit Biolabs,

4 19967

What is boiling point ? & Explain.

2 5834

What is Delay & Dead Volume

2 11484

In method developement or in any analysis if we use small length column for analysis what happen then ? why ?

3 4699

difference between IR& FTIR

Cadila,

4 11941

1 % solution is equal to how much ppm

32 396890


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Un-Answered Questions { Analytical Chemistry }

WHAT IS THE PURPOSE WE USE HCL, CHOPPER, BURNER, MONOCHROMATOR in AAS? PLEASE EXPLAIN BRIEFLY

1068


explain 5 components of gas chromatography ?

665


Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc

254


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1022


What is the diference between residual solvents and organic volatile matter

681






How much is the standard area for glc analysis

934


In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

1609


can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

913




1047


what is definition of validation? which components are followed give detail?

902


what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

1200


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

698


Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

1321


what is difference between zero air gas and o2 gas

6264


Basic principle of ESI?

834