Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

IF HPLC CALIBRATION FAILED THEN WHAT YOU DO

6 36792

Optical Rotation*0.9477*100*200] Assay Of dextrose= ________________________________ 99.8* 200 why Factor=0.9477

Claris Lifesciences, Inven Pharmaceuticals, Levo,

1 15612

How you will select the runtime in HPLC for a drug in method development.

Aurobindo, GVK, Lesanto Laboratories,

6 22174

If compound Pka is 5 then which buffer you will select ?

Avra, GVK,

5 16821

what is the difference between BDS and ODS Columens and both are same or not

Intas, IPQA, Micro Labs, Vasava Engineering Private Limited,

2 73663

difference between HPLC & LC-MS

Lambda,

9 46804

difference between record & document ?

4 14443

in what basis wavelength will select for a compound at initial method development trials

Matrix,

4 12671

How did you conclude that when stressing a compond, all degradation products have eluted in chromatogram?

Matrix,

7 11931

how to prepare working standard in our laboratory aganist reference standard ?

Merit Biolabs, Unichem,

4 25328

What is boiling point ? & Explain.

2 8996

What is Delay & Dead Volume

2 14984

In method developement or in any analysis if we use small length column for analysis what happen then ? why ?

3 7962

difference between IR& FTIR

Cadila,

4 16643

1 % solution is equal to how much ppm

32 428024

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Un-Answered Questions { Analytical Chemistry }

what is mean by peak intigrity?

953

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3129

Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?

2964

if you have given a blank water how you analyse by general analytical techniques?

2032

Why six unit used for precision?

1352

which situation gc hs and gc als require to use?

793

how will you do the prep for unstable componds?

2028

How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1779

How do we fix the sample concentaryion in hplc method development. What is the basis?

1209

In Assy by potentio metry titration method how select MET U ,DET U, SET U,

2172

what is procedure of actual procedure for registration of drug?

2012

How to calibration of the uv spectroscopy and its test?

1196

please explain about aluminium hydroxide assay

1132

If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?

801

we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1872

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