In method developement or in any analysis if we use small length column for an

In method developement or in any analysis if we use small
length column for analysis what happen then ? why ?

Question Posted / tushar

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In method developement or in any analysis if we use small length column for analysis what happen t..

Answer / kishore

retention times, analysis run times, back pressure will
reduced.

May mix closely eluting compounds

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In method developement or in any analysis if we use small length column for analysis what happen t..

Answer / dharmesh bhatt

the question is not very specific, however, if one can use the shorter column for method development, they can optimize the method without sacrificing peak resolution. the theoretical plate and pressure will depend on the type of column & instrument one can select for analysis.
if the shorter column is used for analysis, it will shorten the analysis time and the resolution will sacrifice but again this will depend on the column and instrument.

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In method developement or in any analysis if we use small length column for analysis what happen t..

Answer / qcprashant

Resolution and theoretical plate count will also decrease

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