how require to fix the linearity and accuracy cincentration range?

757

How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1863

From where require to take the RLD sample?

349

for which product require to do content uniformity? what is limit of cu?

407

I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

3076

How would you decide dissolution medium for NCE compound of class I drug

1795

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

3195

Colorimtry

1254

how to qualify the impurity?

400

what is biorelivent dissolution media?

367

Loss of linearity in tkn analysis, possible reasons?

878

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

1575

what is mean by ambient temperature?

479

why salisylic acid not using now days for disdolution calibration?

372

what type of question will ask in the interview of lab chemist.

2967