Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

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inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

675

Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

706

How to set specification of assay, fisdolution and related substances?

838

how to qualify the impurity?

803

what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

856

What is the formula for relative diffrence for standard solution in solution stability in validation?

755

How require to perform linearity as per ANVISA? What are the acceptance criteria?

1285

[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

718

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

785

we can use expired sample for validation and analyst qualification?

760

If vendor having more imp than monograph then how to proceed? and how to set spec?

867

If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

813

how require to set assay concentration for standard and sample?

875

What is dose dumping? why require to do?

885

Please give idea about method development for cleaning method and how maco level establish

706

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Un-Answered Questions { Analytical Chemistry }

A ha tc is actual defination of retention time?

1571

in dissolution why pool sample needed? in which type of drug pool sample need?

3139

Why we use potassium dichromate in uv calibration Exact reason behind it??

1207

1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.

2836

in each media we require to use SLS? how to proceed?

739

What is the requirement for brazil in the analytical method vslidation comparr to ich?

721

why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?

9722

How to choose the which salt is suitable for mobilephase

3193

how many types of balance calibration test?

2263

about method developement in hplc

1677

why salisylic acid not using now days for disdolution calibration?

727

UV and PDA detector, which have less signal to noise ratio?

1097

Please give idea about method development for cleaning method and how maco level establish

706

How to know the estimated LOQ concentration in ppm

1168

how to set sample and standard concentration in RS method?

853

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