Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

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inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

715

Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

741

How to set specification of assay, fisdolution and related substances?

883

how to qualify the impurity?

874

what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

890

What is the formula for relative diffrence for standard solution in solution stability in validation?

802

How require to perform linearity as per ANVISA? What are the acceptance criteria?

1337

[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

792

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

837

we can use expired sample for validation and analyst qualification?

812

If vendor having more imp than monograph then how to proceed? and how to set spec?

935

If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

856

how require to set assay concentration for standard and sample?

923

What is dose dumping? why require to do?

952

Please give idea about method development for cleaning method and how maco level establish

749

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Un-Answered Questions { Analytical Chemistry }

In performance Check of GC Why Hexadecane Peak is Considered

3045

What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7545

What is delay volume?

1395

What is the use of tlc and hplc? And when and where use?

1165

iam usig ph buffers merk. manually how to prepare ?

2278

How would you decide dissolution medium for NCE compound of class I drug

2259

i want model written test paper for the post of analyst in IOCL(indian oil corporation ltd) any one pls help me

2735

Why irmoisture balance is used for corrugated box moisture testing

2404

which batch require to use for analytical method validation?

808

What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

2687

we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1872

if peak get problamatic then what require to do?

805

Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

1820

what is mean by covalidation

785

what is mean by dissolution hydrodynamics?

826

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