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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

what is diffrence between shelf life and expiry date?

11

how you start RS method development when for new product?

13

how you establish the LOQ?

9

in which situation require to use paddle and basket?

8

what is mean by dissolution hydrodynamics?

19

column washing procedure for normal phase and reverse phase?

16

how to convert normal phase hplc to reverse phase and vice versa?

22

if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

22

what is mean by extactable and leachable study?

20

how to calculate elemental impurities?

12

how you fix the limits of impurities?

17

what is mean by nitrosamine impurities?

23

if instrument calibration fails then what require to do?

22

why require the ph, buffer during hplc mobile phase?

35

is it nessesary to do solution stability for 7 days?

23


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Un-Answered Questions { Analytical Chemistry }

how require to select dissolution media? what is discrimination?

15


If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

1500


what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?

2831


If combination product how require to identify which imp is of which api?

11


which situation gc hs and gc als require to use?

8






How to fix the sample conc. in Related substances test by HPLC?

354


Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

889


which are the diffrent batches in the pharmaceuticals?

19


what is diffrence between shelf life and expiry date?

11


What are the primary considerations in extractables and Leachables ?

1524


Why are use silicon oil mr?

393


Why only 1.2 million lux hours require in photostability study?

8


what is biorelivent dissolution media?

12


Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

1183


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1540