If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

397

how pda detector works over uv?

324

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

383

How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1825

for inorganic molecules require to do RS, Assay and disso?

296

what is the difference between potentiometric titration and karl fischer titration?

2495

Why perchloric acid used for potentiometric titration

2213

What should be the level/ Percentage of Arsenic in Arsenic free zinc.

1802

please explain about aluminium hydroxide assay

748

What is the diffrence in japan mkt requirement in analytical method validation over US?

328

WHY pKa value is more important than pH value of the mobile phase in HPLC?

1299

why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

1820

Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

1497

how to set sample and standard concentration in RS method?

407

what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1525