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Analytical Chemistry Interview Questions
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What is mean by PDR?

10

What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

25

Related substance method equivalency on control sample or spiked sample?

10

How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

16

how to develop the icp ms method? Application of icp ms?

16

What is the diffrence in japan mkt requirement in analytical method validation over US?

17

From where require to take the RLD sample?

14

if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

14

in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

17

if you have given one product then how you determine the impurity in that?

3

which are the guidelines for force degradation studies?

9

Is it nessesary all multimedia dissolution require descriminatory?

10

which are the sizes of capsules?

15

if content uniformity passing but dissolution varrying then what is next step?

11

what is mean by least count balance?

18


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Un-Answered Questions { Analytical Chemistry }

why does used dry caffien in HPLC calibration?

1267


Identify problem faced when mass spectroscopy is used with HPLC system ?

1192


if tech transfer fails whay require to do?

14


how require to fix the linearity and accuracy cincentration range?

24


Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

866






1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

900


in which situation ion pair agent require to use?

9


[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

15


how require to set assay concentration for standard and sample?

14


How do we fix the sample concentaryion in hplc method development. What is the basis?

422


Hi sir if any product monograph not given known impurities (may be 5 impurities) specifications then how we require to proceed for inhouse formulation?

12


what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?

8750


what is mean by dissolution hydrodynamics?

19


please explain about aluminium hydroxide assay

458


which lights using during force degradation?

11