Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?

3 8268

what is the need of calulation of RRF of impurity in HPLC analysis?

9 21424

why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?

1 6017




what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

Graviti Pharmaceuticals,

1176

How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

Reddy Labs, Hetero,

1196

only one end point is possible for citric acid and we get 2 end points for di acid why?

Reddy Labs,

3 5290

why kf factor coming 0.5

Alkem Labs,

5 11670

For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?

Alkem Labs,

3 6447




How can v calibrate ftir ? Plz explain me

Cipla,

2 14345

what is the diff betwen calibration and system suitability?

8 13233

Why Methanol used in KF Titration?

Lupin, Glenmark,

15 48180

Why do we use 500ppb sucrose and 500ppb 1,4 benzoquinone in TOC calibration?

Vardhman,

2 5714

why chiral separation?

1 5882

what is main use of primary standards in caliration

Lupin, Nectar Lifesciences, Lee Pharma,

2 2985

what are the important specifications for a Column ?

2 6979


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Un-Answered Questions { Analytical Chemistry }

we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

455


about method developement in hplc

374


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

5387


what is turbidimetric titration?Give 2 examples.

1051


We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?

245






What is the main difference between ODS1 and ODS2 Hplc column.

1746


What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?

2472


could negative ions be produced by bombardment process in mass spectrometry?

177


Why potassium dichromate is used in calibration of uv?

271


why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?

940


how to select short coloum and long coloumn for new molecule

1008


Why dissolution test is not performed in all of the products

1173


using gradient pressure in gas chromatography are not ?using gradient pressure why

2104


why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?

6766


why we are using benzene, anyline in acetic anhdride assay titration method?

807