Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?

3 7953

what is the need of calulation of RRF of impurity in HPLC analysis?

9 20851

why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?

1 5885




what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

Graviti Pharmaceuticals,

1094

How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

Reddy Labs, Hetero,

1134

only one end point is possible for citric acid and we get 2 end points for di acid why?

Reddy Labs,

3 5125

why kf factor coming 0.5

Alkem Labs,

5 11357

For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?

Alkem Labs,

3 6255




How can v calibrate ftir ? Plz explain me

Cipla,

2 13902

what is the diff betwen calibration and system suitability?

8 12744

Why Methanol used in KF Titration?

Lupin,

15 45481

Why do we use 500ppb sucrose and 500ppb 1,4 benzoquinone in TOC calibration?

Vardhman,

2 5485

why chiral separation?

1 5697

what is main use of primary standards in caliration

Lupin, Nectar Lifesciences, Lee Pharma,

2 2764

what are the important specifications for a Column ?

2 6773


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Un-Answered Questions { Analytical Chemistry }

how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1011


How to choose the which salt is suitable for mobilephase

1564


Did anybody have method for acetyl cysteine effervescnce tablet

818


calibrtion procedue of LC-MS

1171


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

1212






AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?

754


what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?

2223


What is the difference between spectro meter and spectro photo meter?

8178


How would you decide dissolution medium for NCE compound of class I drug

630


How will u perform degradation study in detectors other thann PDA in HPLC Methodology

1164


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

939


how can give the expiry period and restadardisation of volumetric solution

1208


Can we interpret accuracy from linearity in method validation?

668


why we should take dst factor for below 1%moisture samples

1301


How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample

860