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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?

3 9982

what is the need of calulation of RRF of impurity in HPLC analysis?

9 24886

why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?

1 6873

what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

Graviti Pharmaceuticals,


How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

Hetero, Reddy Labs,


only one end point is possible for citric acid and we get 2 end points for di acid why?

Reddy Labs,

3 6108

why kf factor coming 0.5

Alkem Labs,

5 13452

For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?

Alkem Labs,

3 7766

How can v calibrate ftir ? Plz explain me


2 15848

what is the diff betwen calibration and system suitability?

8 16221

Why Methanol used in KF Titration?

Glenmark, Lupin,

15 55993

Why do we use 500ppb sucrose and 500ppb 1,4 benzoquinone in TOC calibration?


2 6725

why chiral separation?

1 6861

what is main use of primary standards in caliration

Lee Pharma, Lupin, Nectar Lifesciences,

2 3983

what are the important specifications for a Column ?

2 8019

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Un-Answered Questions { Analytical Chemistry }

What is intact assay method development.....?


What is the difference between purge septum flow and column flow in gas chromatography?


what is partion and column chromatography


what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?


How you develop a method in HPLC?


what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means


what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.


How to calculate coreletion coefficient


How will u perform degradation study in detectors other thann PDA in HPLC Methodology


how to calculate corelation coefficient in G.C Calibration? what is the calculation part?


what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?


how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,


In Dissolution Test why limit is define Q+5% what is the role of +5%.