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what is the purpose of Buffer in any titration?Ex:In determination of hardness of water we use ammonia ammoniachloride buffer in titration with EDTA.Why?
13 91923why KF factor is between 4.5 to 7.5 mg/ml ? why ? why sometime pyridine is used in analysis like in raw material solvent like acetone etc?
11 72087what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?
4489When performing Moisture content how to you say only Methanol react with water not product Explain?
2 10368How we develop a method by HPLC for unknown compound,if we got three peaks with same response then how we can find out which one is our desired compound's peak without taking help of LC MS.
4 15021In case of dissolution test, if there is variation within 6 individual units however the batch is complying as per S1 criteria, is it necessary to do investigation for the same? What should be the criteria for such variation?
2 5651What is the difference between bulk property detectors and Solute property detectors vivimed labs limited
3 17557IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF THE COMPOUNDS PKA. WHAT IS THE CONDITION
2 10441IN DISSOLUTION TEST S1AND S2 AND S3 CONDITIONS ALL ARE FAILED THEN WHAT IS THE DESSICION U CAN TAKE
12 28639Post New Analytical Chemistry Questions
if identification threshold crosses the limits then what next step?
calibrtion procedue of LC-MS
what is biorelivent dissolution media?
if you have given one product then how you determine the impurity in that?
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
Why perchloric acid used for potentiometric titration
function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
how you start the solubility study?
is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth
if content uniformity passing but dissolution varrying then what is next step?
why does used dry caffien in HPLC calibration?
in sampling of raw material which side is pasted sampled labels
In which situation we require to analytical method validation of excipient?
How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?
