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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

what is the purpose of Buffer in any titration?Ex:In determination of hardness of water we use ammonia ammoniachloride buffer in titration with EDTA.Why?

Amity, Prakriti, Sr Comunications,

13 82701

why KF factor is between 4.5 to 7.5 mg/ml ? why ? why sometime pyridine is used in analysis like in raw material solvent like acetone etc?

Aurobindo, GVK, Sohan Healthcare,

11 50914

what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

Neuland,

3467

What is the Column Endcaping in HPLC ?

Aptuit Laurus,

3 11996

When performing Moisture content how to you say only Methanol react with water not product Explain?

Orchid,

2 8163

give me method of calculating co relation of coefficient for HPLC,SOR & ANY OTHER

1 2494

difference between pH & pOH ?

4 18652

what r the reasons to get peak telling?

Cipla,

6 11990

How we develop a method by HPLC for unknown compound,if we got three peaks with same response then how we can find out which one is our desired compound's peak without taking help of LC MS.

Apotex, Kemwell,

4 11584

In case of dissolution test, if there is variation within 6 individual units however the batch is complying as per S1 criteria, is it necessary to do investigation for the same? What should be the criteria for such variation?

1 3387

What is the difference between bulk property detectors and Solute property detectors vivimed labs limited

3 13452

IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF THE COMPOUNDS PKA. WHAT IS THE CONDITION

Dr Reddys, Reddy Labs,

2 8225

What are the limits for uniformity dosage content for tablets and capsules

Micro Labs,

5 17734

WHAT IS THE USAGE OF REFRACTIVE INDEX IN PHARME FIELD

3 7253

IN DISSOLUTION TEST S1AND S2 AND S3 CONDITIONS ALL ARE FAILED THEN WHAT IS THE DESSICION U CAN TAKE

Cipla,

12 20265


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Un-Answered Questions { Analytical Chemistry }

What is related substance by HPLC impurity limits as per USP?

43


Basic principle of ESI?

1160


How to fix the sample conc. in Related substances test by HPLC?

113


What is similarity factor and its use in api strength?

206


what is the origin to prepare standard operating procedure

1294






Why use only methanol,used determinationof moisture content not use other solvents

230


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

1655


Why irmoisture balance is used for corrugated box moisture testing

1394


A ha tc is actual defination of retention time?

544


How to calculate coreletion coefficient

562


What is delay volume?

191


How to do regeneration of Metacarb Pb plus column?

1622


Why we used in n-butyl acetate water content terminology while in ethyl acetate we used moisture content terminology?

902


Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?

1566


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1322