what is the purpose of Buffer in any titration?Ex:In determination of hardness of water we use ammonia ammoniachloride buffer in titration with EDTA.Why?
13 87324why KF factor is between 4.5 to 7.5 mg/ml ? why ? why sometime pyridine is used in analysis like in raw material solvent like acetone etc?
11 65492what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?
3979When performing Moisture content how to you say only Methanol react with water not product Explain?
2 9207How we develop a method by HPLC for unknown compound,if we got three peaks with same response then how we can find out which one is our desired compound's peak without taking help of LC MS.
4 13358In case of dissolution test, if there is variation within 6 individual units however the batch is complying as per S1 criteria, is it necessary to do investigation for the same? What should be the criteria for such variation?
2 4363What is the difference between bulk property detectors and Solute property detectors vivimed labs limited
3 15447IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF THE COMPOUNDS PKA. WHAT IS THE CONDITION
2 9405IN DISSOLUTION TEST S1AND S2 AND S3 CONDITIONS ALL ARE FAILED THEN WHAT IS THE DESSICION U CAN TAKE
12 24919Post New Analytical Chemistry Questions
what is definition of validation? which components are followed give detail?
why require to add enzymes in capsules dissolution only? is it require to tablet also?
in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?
How to fix the sample conc. in Related substances test by HPLC?
In which situation we require to analytical method validation of excipient?
how require to interprit the method precision data of hptlc?
How we choose the mobile phase for method development.?
in api coa contains only process impurities and in product coa contains degradation impurities?
What is a difference between potency and purity?
I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?
why we are using hexane in calibration of number of drop per mL
What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?
on saturation solubility study data how we can find out the bcs class of drug?
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
