what is poarimeter, why it is used in pharma,and explain
briefly about polarimeter?
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Answer / kirit h kaila
A polarimeter [1] is a scientific instrument used to measure the angle of rotation caused by passing polarized light through an optically active substance.[2]
Some chemical substances are optically active, and polarized (unidirectional) light will rotate either to the left (counter-clockwise) or right (clockwise) when passed through these suIsolating and identifying unknowns crystallized from various solvents or separated by high performance liquid chromatography (HPLC).
Evaluating and characterizing optically active compounds by measuring their specific rotation and comparing this value with the theoretical values found in literature.
Investigating kinetic reactions by measuring optical rotation as a function of time.
Monitoring changes in concentration of an optically active component in a reaction mixture, as in enzymatic cleavage.
Analyzing molecular structure by plotting optical rotatory dispersion curves over a wide range of wavelengths.
Distinguishing between optical isomers.bstances. The amount by which the light is rotated is known as the angle of rotation.
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Answer / ganesh d
Polarimeter is the one of analytical instrument, it is used
to determine the angle of rotation of drug substance,
either dextro or leavo rotatory and also determine the
purity of drug substance.
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Answer / ram krishna
Polarimeter is a instruments that use to determine the compound is dextro or levo rotatrey
Polarimeter is cosist of sodium lamp and sampler holder with a Polarimeter tube 1 or 2dcm fill the sample in this tube instruments is on solution prepaired and fill in Polarimeter tubes and note down the reading automatically Polarimeter is available in market it gives a optically active material
A compound which is presente chiral corban is optically active
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What is Standard deviation
My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards
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