what is poarimeter, why it is used in pharma,and explain
briefly about polarimeter?

Answers were Sorted based on User's Feedback



what is poarimeter, why it is used in pharma,and explain briefly about polarimeter?..

Answer / kirit h kaila

A polarimeter [1] is a scientific instrument used to measure the angle of rotation caused by passing polarized light through an optically active substance.[2]
Some chemical substances are optically active, and polarized (unidirectional) light will rotate either to the left (counter-clockwise) or right (clockwise) when passed through these suIsolating and identifying unknowns crystallized from various solvents or separated by high performance liquid chromatography (HPLC).
Evaluating and characterizing optically active compounds by measuring their specific rotation and comparing this value with the theoretical values found in literature.
Investigating kinetic reactions by measuring optical rotation as a function of time.
Monitoring changes in concentration of an optically active component in a reaction mixture, as in enzymatic cleavage.
Analyzing molecular structure by plotting optical rotatory dispersion curves over a wide range of wavelengths.
Distinguishing between optical isomers.bstances. The amount by which the light is rotated is known as the angle of rotation.

Is This Answer Correct ?    7 Yes 0 No

what is poarimeter, why it is used in pharma,and explain briefly about polarimeter?..

Answer / ganesh d

Polarimeter is the one of analytical instrument, it is used
to determine the angle of rotation of drug substance,
either dextro or leavo rotatory and also determine the
purity of drug substance.

Is This Answer Correct ?    2 Yes 1 No

what is poarimeter, why it is used in pharma,and explain briefly about polarimeter?..

Answer / ram krishna

Polarimeter is a instruments that use to determine the compound is dextro or levo rotatrey
Polarimeter is cosist of sodium lamp and sampler holder with a Polarimeter tube 1 or 2dcm fill the sample in this tube instruments is on solution prepaired and fill in Polarimeter tubes and note down the reading automatically Polarimeter is available in market it gives a optically active material
A compound which is presente chiral corban is optically active

Is This Answer Correct ?    0 Yes 1 No

Post New Answer

More Analytical Chemistry Interview Questions

Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

0 Answers   Petronas, Shanghai Ocean University,


why require to do water content for drug product?

0 Answers  


If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

0 Answers  


if you have given one product then how you determine the impurity in that?

0 Answers  


Which std. used for standrdisation of ZnSO4?

1 Answers  






How will you separate Colorless compound Using Column Chromatography?

4 Answers   Delhi University, VPHS,


what is the difference of use of LOD test and Karl Fischer titra.?

15 Answers  


Explain the relations between number of carbon atoms in alkanes and retention time ?

0 Answers   College School Exams Tests,


how can standardized of HCl of 0.1 N

7 Answers  


What is difference between" LOD" AND "VACCUME LOD"

2 Answers  


If mass balance is not passing in forced degradation in method validation that method is suitable or not?

1 Answers   Aurobindo, Dr Reddys, Reddy Labs, Wockhardt,


Why 10%,20%,30% Sucrose solution is used for the calibration of polarimeter?

5 Answers   Cipla, LGC Promochem,


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (342)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1387)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)