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what is poarimeter, why it is used in pharma,and explain
briefly about polarimeter?
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Answer Posted / kirit h kaila
A polarimeter [1] is a scientific instrument used to measure the angle of rotation caused by passing polarized light through an optically active substance.[2]
Some chemical substances are optically active, and polarized (unidirectional) light will rotate either to the left (counter-clockwise) or right (clockwise) when passed through these suIsolating and identifying unknowns crystallized from various solvents or separated by high performance liquid chromatography (HPLC).
Evaluating and characterizing optically active compounds by measuring their specific rotation and comparing this value with the theoretical values found in literature.
Investigating kinetic reactions by measuring optical rotation as a function of time.
Monitoring changes in concentration of an optically active component in a reaction mixture, as in enzymatic cleavage.
Analyzing molecular structure by plotting optical rotatory dispersion curves over a wide range of wavelengths.
Distinguishing between optical isomers.bstances. The amount by which the light is rotated is known as the angle of rotation.
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