Which parameter require to do for analytical method equivalency?


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Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me

5 Answers   Ordain Solutions,


what is mean by dissolution hydrodynamics?

0 Answers  


If combination product how require to identify which imp is of which api?

0 Answers  


why we are analyzing purity on HPLC why not in gc

3 Answers   Aurobindo, Reddy Labs,


Why potassium dichromate is used in calibration of uv?

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what split ratio in gas chromatography.

9 Answers   Cipla, Glochem,


what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

0 Answers   DRL, Laurus,


From where require to take the RLD sample?

0 Answers  


acceptance criteria for ph meter, hplc detector,pump,injector,oven when we calibrate.

3 Answers  


in uv visible spectroscopy calibration why we are using potasium dichromate and tolune

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