Answer / tushar

Assay is quantitatively determination of the amount main
component of a sample present in substance.
Purity is determination of impurities present in substance.

Answer / jay jadhav

Assay is the quantitative determination of the amount of a
component in a sample.
Purity is the determination of the impurities in the
sample. It can be quantitative, semi-quantitative or
qualitative.
For example : if you dissolve 4 grams of compound A (with
no impurities in it) in 6 grams of water, you get a
solution of compound A with 100% purity and 40% assay.

Answer / shyam

in assay we estimate the analyte
content. in this caliculation we use area. this is
quantitative analysis.
In purity testing we estimate the analyte concentration.in
this caliculation we use percentage of area.this is
qualitative analysis.

Answer / m.g. madhu babu

1. Assay will vary w.r.t. the sample quantity.
Irrespective of sample quantity final result should be the
same. (No change in the result).
2. For assay, reference std. must. No ref. std. will be
used for purity.
3. Assay can be calculated by chemical, HPLC, UV, IC, etc.,
where as purity by using chromatography only.
4. Mainly assay will be calcluated for API's, where as
purity for RM's & IM's.

Answer / pharmainterview

Purity : indicates how pure our analyte is.

Assay: indicates how much of our analyte is.

Potency: indicates how potent(the original content) our
analyte is.

Regards
pharmainterviewquestions.blogspot.in

Answer / arun tiwari

In assay we estimate the exact amount of substance present
in sample matrix w.r.t standard of known potency.


Potency is a measure of the activity of a drug in a
biological system and assay of std refered as potency.

Purity is the test to calculate the content of impurities
present in sample matrix.All impurities can not be analyse
by single method.

Answer / gokul yeole

Assay is quantitatively determination of the amount main
component of a sample present in substance.
Purity is determination of impurities present in substance

Answer / raja

Purity is comparison of sample profile with Blank.
Assay is a comparison of sample with Standard.
Purity is except blank how it is...
Assay is compared to std how much it is..

Answer / amit

Purity= Assay-(Imps+ Res sol+ water contents+ other salt
factor etc)
Assay - chromatographic purity

What is FFA, PV, and PAV value in oil.

1 Answers   Nestle,

What is difference between assay by Hplc and uv

2 Answers   Aizant, Fredun Pharmaceuticals, Hetero, Marksans Pharma,

Why sulpuric acid only used to ROI but not used nitric acid and some other acids?

7 Answers   Cadila, Laurus, Ranbaxy,

In which cases factor of KF Reaget got higher side

2 Answers  

Why Urasil and Caffeine use for HPLC wavelength accuracy calibration. which is most suitable, Why? other than these which can be used?

7 Answers   Cipla,

When recording an IR spectrum in the lab, we take no special precautions to account for the presence of oxygen, nitrogen, or argon in the air. What are the consequences of this?

1 Answers  

How do we fix the sample concentaryion in hplc method development. what is the basis?Thanks in advance

4 Answers   DRL, Glenmark, Orchid,

What will be the effect on HPLC analysis result if three mobile phases given separately through three valves and same proportion mixed together and given by one valve?

1 Answers   LOIL,

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

0 Answers   Micro Labs, VMSRF,

how much mass should be there in volumetric flask while in preparation of sample for assay? 

0 Answers   Reddy Labs,

In UV calibration we use Holmium perchlorate solution made in 1.4M perchloric acid The question is that 1.4 M perchloric acid we make is it in water or glacial acetic acid?

4 Answers  

Why 1800 ml of dissolution media used In Carbamazepine ER USP Tablets But other drug only 900 ml Media Used ?

1 Answers   Torrent Pharma,