we calibrate HPLC once in 6 months while iam doing
calibration i came to know that calibration was failed.
then how can i justify that the samples analyzed on the
system during this 6 months was wright? how can i forward in
to the next step for those batches?
- 5 Answers
- 11072 Views
- I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / ravi narwade
Whenever we are doing any analysis we are performing the
system suitability test for it, and if the "SST" is passing
no one will raise the question on analysis of samples on
the instrument which fails in calibration.
| Is This Answer Correct ? | 31 Yes | 8 No |
Answer / nirchana
if u hv doubt ..thn u can check previous sample tht result u known..tht means any std sample thn match with recent sample
| Is This Answer Correct ? | 2 Yes | 2 No |
Answer / k l reddy
Need not to analyze all previous batches but you should
analyze 6 previous batches(recent batches of before
calibration)on different system(which is qualified) and
compare the results with old results. Fallow the same
prociser until the resukts matched with old results.
| Is This Answer Correct ? | 2 Yes | 2 No |
Answer / sasikala
Need not to analyze all previous batches but you should
have internal sop which describes how many batches
(immediate previous batches) to be analyzed and how to be
compared. But this anwser not complete one for you.
| Is This Answer Correct ? | 1 Yes | 4 No |
Answer / pankaj punjabi
After 6 month calibration is failed,So you have to
reanalyse the previous batches which is analyse for last 6
month.and comapre the results.then only it is justified.
| Is This Answer Correct ? | 2 Yes | 16 No |
what is DIPE limit in residual solvent?
why we calibrate ph meter and balance daily.....but hplc and uv requires quaterly?
What is the difference between uplc and hplc
4 Answers AAU Assam Agricultural University, Hetero,
How did you conclude that when stressing a compond, all degradation products have eluted in chromatogram?
How to calculate lamp energy in hplc?
Why Ethanol is Used for Standardization of GC Head space?
0 Answers Anuh Pharma, Cipla, Finar Chemicals, Hetero, Sun Pharma,
what is mean by assay?
What is the difference between Chromatograhic Purity And Related substances
What is column dead volume?
Why chromic acid wash is not recommended by USP for glassware cleaning?
why chiral separation?
why we multiply 1000 in the determination of kf factor ?
3 Answers Stellence Pharm Science,
Organic Chemistry 
