Answer / vairamuthu

First of all we need to know what polar molecules are.Some elements have a greater tendency to attract electrons than the other ie they're more electronegative. So when in covalent moelcule a pair of less electronegative and a more electronegative element is present, the electrons shift from their mean position to slightly towards more electronegative. Thus the elements acquire slight charge. This is known as polar bond. The molecule so formed is known as polar molecule. e.g. In HCl, Cl is more electronegative and attracts electron towards itself, Cl acquires slight negative charge and H acquires slight positive charge. Similarly in water, Oxygen acquires negative charge and hydrogen positive
So now we can define the required as Polar solvent are those solvents which are constituted of polar molecules. e.g. Water, HCl
Non polar solvents are those solvents which are made up of non polar molecules. e.g. Carbon Disulphide, Carbon tetrachloride

Answer / ektaa vashishth

Polar solvents means having negative and positive charge ions.
whereas non polar solvents does not having negative and
positive charge ions.

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

0 Answers  

---

reasons for negative peaks in chromatography

5 Answers   DRL,

---

if you get peak in blank then what require to do?

0 Answers  

---

in which situation require to use paddle and basket?

0 Answers  

---

why we cannot analysis below 200nm in u.v?

2 Answers  

---

What is difference between Potency & purity

3 Answers  

---

how peak can be sharp in hplc when it is come flat

6 Answers   Graviti Pharmaceuticals,

---

What is Temperature ?

2 Answers   Reddy Labs,

---

inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

0 Answers  

---

could negative ions be produced by bombardment process in mass spectrometry?

0 Answers  

---

What r the limitatoins of uv visible spectroscopy ? Why Water use in blank standard for uv visible spectroscopy ?

4 Answers   Cipla, Reddy Labs,

---

solvents used in NMR

2 Answers   Laurus,

---