Any molecule is filing for ANDA purpose, what are the dissolution requirements / specifications needed ?
What is Endcapped Hplc column2 7653
I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?
what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?2570
why does used dry caffien in HPLC calibration?
How to choose the which salt is suitable for mobilephase
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
What is the principle of Thermal conductivity detector and FID?
How do we fix the sample concentaryion in hplc method development. What is the basis?
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
How to start the dissolution development for unknown tab?
Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?
What is similarity factor and its use in api strength?
what is peak purity and its formula
WHY given much noise PDA dector then VWD Dector
Why dissolution test is not performed in all of the products
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
Loss of linearity in tkn analysis, possible reasons?
In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?