Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What are the different types of columns used in HPLC

Wockhardt,

3 9168

In HPLC when we use Isocratic method, Gradient method in hplc?

Pharmaceutical,

8 14608

Any molecule is filing for ANDA purpose, what are the dissolution requirements / specifications needed ?

IPCA,

1 4064




What is Endcapped Hplc column

2 6803

Why we more noise in PDA detector compared to UV detector?

Aurobindo,

1 8845

if the purity is 99.9%,is need to do assay?

Reddy Labs,

3 11474

What is the difference between specified impurity and Identified impurity

Glenmark,

3 10216

What is the difference between specified impurity and Identified impurity

Merchant Navy,

1 3067




how do you established the RRF for unknown impurity

Square Pharma,

3 8072

I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?

AMRI,

3 6615

How we will choose pH of a mobile phase if analyte pKa value is 4

Laurus, Celon Labs,

2 8273

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

Laurus, DRL,

2285

Which column is more polar, C8 or C18?

Glenmark, Cipla, Laurus, Torrent Power,

6 21148

what is the difference between heavy metals and sulphated ash

Aurobindo,

2 12194

what is difirence b/w ROI&ROE

Pfizer,

1 6929


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Un-Answered Questions { Analytical Chemistry }

Why potassium dichromate is used in calibration of uv?

417


4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations

1355


how will you do the prep for unstable componds?

727


What is third generation HPLC Columns?

783


How to do regeneration of Metacarb Pb plus column?

1338






For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

23


how to select short coloum and long coloumn for new molecule

1099


What is the difference between spectro meter and spectro photo meter?

8680


what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?

2363


How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

453


How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?

1921


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

438


in dissolution why pool sample needed? in which type of drug pool sample need?

1898


What is intact assay method development.....?

1192


EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE

1404