Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What are the different types of columns used in HPLC

Wockhardt,

2 8588

In HPLC when we use Isocratic method, Gradient method in hplc?

Pharmaceutical,

8 13740

Any molecule is filing for ANDA purpose, what are the dissolution requirements / specifications needed ?

IPCA,

1 3874




What is Endcapped Hplc column

2 6418

Why we more noise in PDA detector compared to UV detector?

Aurobindo,

1 8325

if the purity is 99.9%,is need to do assay?

Reddy Labs,

3 11039

What is the difference between specified impurity and Identified impurity

Glenmark,

3 9197

What is the difference between specified impurity and Identified impurity

Merchant Navy,

1 2582




how do you established the RRF for unknown impurity

Square Pharma,

3 7683

I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?

AMRI,

2 6315

How we will choose pH of a mobile phase if analyte pKa value is 4

Laurus, Celon Labs,

2 7837

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

Laurus, DRL,

2146

Which column is more polar, C8 or C18?

Glenmark, Cipla, Laurus, Torrent Power,

6 19532

what is the difference between heavy metals and sulphated ash

Aurobindo,

2 10943

what is difirence b/w ROI&ROE

Pfizer,

1 6606


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Un-Answered Questions { Analytical Chemistry }

why we use sodium salicylate in uv light calibration at TLC chamber

4758


Explain the relations between number of carbon atoms in alkanes and retention time ?

576


USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

504


Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?

1404


are there in uv lamb that is chractrestic for wavelenghth 205 nm ?????

673






please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

274


How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

1165


how to select short coloum and long coloumn for new molecule

952


Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?

933


How will u perform degradation study in detectors other thann PDA in HPLC Methodology

1185


How can we calculate offset value pH measurment

149


How to define samples weight in moisture content

82


What is the principle of Thermal conductivity detector and FID?

1355


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

254


Which std. used for standrdisation of ZnSO4?

988