Interested to Buy Any Domain ? << Click Here >> for more details...
Why we more noise in PDA detector compared to UV detector?
- 1 Answers
- 11645 Views
- Aurobindo, I also Faced
- E-Mail Answers
Answer / anil
There is no Integration function in the conventional UV-Vis spectrophotometer which
accumulates the signal. For example, the total required time will be 1000 sec. for 1000 data
points and it takes 1 sec. to measure one datum. In this case, all 1000 data have the same signal
to noise ratio (S/N).
But in a PDA instrument which has a 1000 photodiode array, 1000 data points can be
measured in 1 sec. and it would take 1/1000 sec. to achieve the same result obtainable in 1 sec.
in a conventional instrument. Therefore, when the same sample is measured for 1000 sec in a
PDA instrument, the signal is accumulated and is 1000 times greater than when measuring for 1
sec. The noise will be 10001/2
. This means that the S/N ratio is improved by 10001/2
.
This resulting benefit of fast data acquisition is termed Felgett’s S/N Advantage or
Multichannel Advantage
| Is This Answer Correct ? | 10 Yes | 1 No |
How to select buffer for HPLC mobile phase
4 Answers Cadila, Cipla, Lupin,
How we can determine OOT limit in Stability
how to calculate corelation coefficient in G.C Calibration? what is the calculation part?
what is protocol ? plz Explain me
What is the acceptance criteria for moisture balance when calibrated with sodium sulfate
how v can identify functional groups by wet techniques?
Why monograph of hplc coming upperside of drift but in IR monograph coming in drift side?
why we use kbr as constant in the FTIR ?
what is the difference of use of LOD test and Karl Fischer titra.?
principle of UV , PDA , RI detector in HPLC
what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me
0 Answers Graviti Pharmaceuticals,
Dear sir, This is R.Kadambavadani working in a pharma industry. while doing RS analysis of ibuprofen API, unknown peak eluting some times in the 0.6 Min RT. Kindly send me what is the exact reason behind that. also am using ACN the mobile phase.
Organic Chemistry 
