Analytical Chemistry Interview Questions
Questions Answers Views Company eMail


Apotex, Micro Labs, Rene,

1 12887

What is the Baseline in HPLC.

Teva API,

2 8970

Why dst is used in kf for factor determination less than 1

Reddy Labs, Sun Pharma,

4 12052

why should we calibrate pH meter with 4,9.2 and 7.4 buffers particularly?

Celon Labs,

5 9104

why inject diluted standard solution in related substance analysis by HPLC?

Sun Pharma, Biocon,

2 11238

What is the Calcultion of S/N Ratio.

2 7870

Principle of HPLC in one sentance


8 11482

Why are using in Hi,zero air, Ni gass are used GC

Aurobindo, ELBS, Vimta Labs,

5 9028

what is the balance drift?

Torrent Pharma,

2 8367

Retention time & Relative Retention time Definition & between difference? How to Calculate response factor(RF) & relative response factor(RRF)?

MSN Pharma, Titan,

3 14179

why are using toluene in uv calibraion in resolution performance

MSN Pharma,

2 8054

why we make titiration of Iron with EDTA ?

Cipla, Sitec Labs,

1 6484

What is difference b/w IR&NIR


1 3617

Why does boiler drum ph maintain from 9.5 to 10.2

1 4945

What is the definition of water content or moisture content,what is the procedure going on w.c amalysis?

Cipla, KIYI,

1 7719

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Un-Answered Questions { Analytical Chemistry }

which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate


what is procedure of actual procedure for registration of drug?


Why sodium hydroxide used for maintain pH of phosphate buffer


why equlirium conatant of water have 14 value


In Dissolution Test why limit is define Q+5% what is the role of +5%.


How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium


USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.


For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.


What is gelatinization?


What is diffrence between extractable volume and deliverable volume? Answer pls