Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

what is rs test why we are perfoming rs test

2 5816

In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

Orchid,

1872

What is difference between silica used in TLC and HPLC column

Cipla, Meghmani Organics,

4 13304




Why Urasil and Caffeine use for HPLC wavelength accuracy calibration. which is most suitable, Why? other than these which can be used?

Cipla,

7 12357

When we r doing processing method for sst in Empower software by HPLC, What value has to give in void volume and as per which pharmacopia!

Micro Labs, Mylan,

4 9046

what is use of acetonitrile compare to methanol in RP-HPLC Method devlopment

Orchid, Neuland,

7 16430

is a bonded water molecule in an organic material can be easlisy and accuractly determined by KF rather than LOD

2 4719

How to know HPLC column performance?

Meghmani Organics,

4 8142




What is heavy water

Meghmani Organics,

2 5538

What will be the effect on HPLC analysis result if three mobile phases given separately through three valves and same proportion mixed together and given by one valve?

LOIL,

1 2850

Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

1375


why you are using benzoic acid for water content determination in TEA

2 5005

difference between instrumenent and equipment

6 8398

mixed 1.0 ml of methanol and 1.0 ml of toluene and injected in gas chromatography.will you prove that both solvents are in the ratio 1:1(not by area normalization)

1 1451


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Un-Answered Questions { Analytical Chemistry }

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

254


what is procedure of actual procedure for registration of drug?

570


If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

914


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

979


what is the extinction coefficient for Indomethacin or at 319nm wave length.

2495






function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

1162


What is column in chromatography?

750


In Karl Fischer titration,What is the situation if the material tested is only soluble in water,and not soluble in the common solvents used such as methanol ?? [e.g. Iron III Hydroxide polymaltose]

1442


How to define samples weight in moisture content

81


what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

1136


Can we interpret accuracy from linearity in method validation?

699


what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

2146


Which std. used for standrdisation of ZnSO4?

987


How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample

926


How would you decide dissolution medium for NCE compound of class I drug

664