Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 55817

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 6523

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2085

why using buffers in hplc inteed of water

5 12231

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 2457

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 4771

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 5592

In specificity what parametrs are consider why that parametrs

2 5820

ash or residue in that what will be there.

3 5275

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 2672

What is difference between oos

Gennex,

7 25946

what is the differance between Analytical and semi micro balance?

2 12598

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10105

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 6284

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 13123


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Un-Answered Questions { Analytical Chemistry }

if rsd failed then what require to do?

335


how to decide for one product require water content or LOD?

333


in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

342


for heavy metal test lead used in which form pure form or any other form for preparation of lead standard sol

5320


how to get accurate result for Residue on evaporation in purified water

1130






what is classification of elemental impurities? what is risk assement in elemental impurities?

350


what is the purge flow & how to calculate

1987


Which is the highly polar and highly non polar column in HPLC?

1791


What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1159


some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2110


Related substance method equivalency on control sample or spiked sample?

309


which situation gc hs and gc als require to use?

306


Hi sir if any product monograph not given known impurities (may be 5 impurities) specifications then how we require to proceed for inhouse formulation?

288


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1187


effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?

334