Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 57696

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 7559

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2668

why using buffers in hplc inteed of water

5 14670

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 3201

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 5593

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 6995

In specificity what parametrs are consider why that parametrs

2 7113

ash or residue in that what will be there.

3 6794

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 3522

What is difference between oos

Gennex,

7 28456

what is the differance between Analytical and semi micro balance?

2 13927

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 11128

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 7472

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 14978

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Un-Answered Questions { Analytical Chemistry }

what is mean by peak intigrity?

1029

Why a1% value is used for some product ? What is the criteria for selection a1% value ?

2399

can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

2228

why require to add enzymes in capsules dissolution only? is it require to tablet also?

727

We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1970

how to qualify the impurity?

946

is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

2222

how you start RS method development when for new product?

780

what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR

9301

Difference between the quantitative analysis and qualitative analysis?

1248

WHY pKa value is more important than pH value of the mobile phase in HPLC?

1814

how you determine moist.of NaOH sol or NaOH flacks

2269

what is mean by dissolution hydrodynamics?

891

How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2633

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

890

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