Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 43381

Why pH Range has been fixed as 0 to 14 ?

Matrix, Akums, Cipla, SUN,

1 3810

How you develop a method in HPLC?

Wockhardt, Perrigo, CU,


why using buffers in hplc inteed of water

5 7729

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 1043

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 2942

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Reddy Labs, Dr Reddys, IPCA,

1 2493

In specificity what parametrs are consider why that parametrs

2 3517

ash or residue in that what will be there.

1 2799

How can we determine Moisture content of HI?

Cipla, Reddy Labs,


What is difference between oos


7 19627

what is the differance between Analytical and semi micro balance?

2 8499

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 7787

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 2958

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 9401

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Un-Answered Questions { Analytical Chemistry }

can i use hplc detector to uplc and why?


Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.




Did anybody have method for acetyl cysteine effervescnce tablet


What is third generation HPLC Columns?


What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?


about method developement in hplc


why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?


how to calibrate hplc & gc


what is the identification test of volatile substance? what is volatile compound?


Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18


what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?


when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.


What is gelatinization?