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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 54751

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 6055

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

1911

why using buffers in hplc inteed of water

5 11329

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 2170

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 4434

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 4964

In specificity what parametrs are consider why that parametrs

2 5224

ash or residue in that what will be there.

3 4715

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 2299

What is difference between oos

Gennex,

7 24945

what is the differance between Analytical and semi micro balance?

2 12045

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 9699

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 5445

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 12398


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Un-Answered Questions { Analytical Chemistry }

WHAT IS THE PARAMETER FOR THE SELECTION OF MOBILE PHASE IN HPLC?

467


Why use only methanol,used determinationof moisture content not use other solvents

598


How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

2612


why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

1612


What is the diference between residual solvents and organic volatile matter

1284






can i use hplc detector to uplc and why?

1645


if you given one product then which tests you will perform?

122


iam usig ph buffers merk. manually how to prepare ?

1568


WHY pKa value is more important than pH value of the mobile phase in HPLC?

1058


how require to set assay concentration for standard and sample?

105


how you confirm the assay method?

106


Did anybody have method for acetyl cysteine effervescnce tablet

1612


on the basis of bcs class how to proceed the solubility?

100


why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?

8442


what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

3778