Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 55932

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 6569

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2117

why using buffers in hplc inteed of water

5 12339

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 2500

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 4823

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 5686

In specificity what parametrs are consider why that parametrs

2 5879

ash or residue in that what will be there.

3 5353

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 2716

What is difference between oos

Gennex,

7 26066

what is the differance between Analytical and semi micro balance?

2 12676

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10171

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 6363

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 13223


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Un-Answered Questions { Analytical Chemistry }

why we are using hexane in calibration of number of drop per mL

1201


Is it nessesary all multimedia dissolution require descriminatory?

375


How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1345


What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8358


Loss of linearity in tkn analysis, possible reasons?

841






what is mean by dissolution biowaiver study?

364


how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,

2083


Why irmoisture balance is used for corrugated box moisture testing

1973


can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

1739


why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?

1802


Explain the relations between number of carbon atoms in alkanes and retention time ?

1667


What is delay volume?

898


we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1393


How doing qbd practically?

473


why does used dry caffien in HPLC calibration?

1609