Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 55730

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 6487

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2065

why using buffers in hplc inteed of water

5 12173

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 2432

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 4748

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 5537

In specificity what parametrs are consider why that parametrs

2 5785

ash or residue in that what will be there.

3 5211

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 2639

What is difference between oos

Gennex,

7 25838

what is the differance between Analytical and semi micro balance?

2 12543

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10067

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 6227

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 13054


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Un-Answered Questions { Analytical Chemistry }

Why a1% value is used for some product ? What is the criteria for selection a1% value ?

1856


how much mass should be there in volumetric flask while in preparation of sample for assay? 

2045


what type of questions asked on analytical balance and also give answers................all pharma companies?

11696


Did anybody have method for acetyl cysteine effervescnce tablet

1804


How doing qbd practically?

416






For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

1778


How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

3579


analytical method validation require to with respect to release specification or shelf life specification?

269


which batch require to use for analytical method validation?

321


How do we fix the sample concentaryion in hplc method development. What is the basis?

666


function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

2054


Why sodium hydroxide used for maintain pH of phosphate buffer

1816


What is the diffrence in japan mkt requirement in analytical method validation over US?

279


give clarity of linearity and range in method validation

1846


what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?

3171