Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 48336

Why pH Range has been fixed as 0 to 14 ?

Matrix, Akums, Cipla, SUN,

1 4628

How you develop a method in HPLC?

Wockhardt, Perrigo, CU,

1357




why using buffers in hplc inteed of water

5 8665

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 1326

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 3417

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Reddy Labs, Dr Reddys, IPCA,

2 3229

In specificity what parametrs are consider why that parametrs

2 3970




ash or residue in that what will be there.

2 3279

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 1288

What is difference between oos

Gennex,

7 21280

what is the differance between Analytical and semi micro balance?

2 9748

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 8486

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 3697

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 10377


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Un-Answered Questions { Analytical Chemistry }

Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

1525


What is the diference between residual solvents and organic volatile matter

762


what is the purge flow & how to calculate

1261


WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

935


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

1390






for heavy metal test lead used in which form pure form or any other form for preparation of lead standard sol

3763


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

5614


what is the principle involved in turbidometry and nephelometry ?

2638


What is column in chromatography?

882


We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?

353


Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?

1736


Tell me about analytical method validation in QC

2245


some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

1229


what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

3176


How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

1988