Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 46662

Why pH Range has been fixed as 0 to 14 ?

Matrix, Akums, Cipla, SUN,

1 4320

How you develop a method in HPLC?

Wockhardt, Perrigo, CU,


why using buffers in hplc inteed of water

5 8260

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 1213

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 3256

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Reddy Labs, Dr Reddys, IPCA,

2 2908

In specificity what parametrs are consider why that parametrs

2 3792

ash or residue in that what will be there.

2 3106

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 1102

What is difference between oos


7 20560

what is the differance between Analytical and semi micro balance?

2 9222

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 8155

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 3321

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 10018

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Un-Answered Questions { Analytical Chemistry }

My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards


What is the main difference between ODS1 and ODS2 Hplc column.


what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me


Why irmoisture balance is used for corrugated box moisture testing


what type of questions asked on analytical balance and also give answers................all pharma companies?


why we should take dst factor for below 1%moisture samples


Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.


what is third integration


function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?


How to define samples weight in moisture content


Tell me something about Vitamin A test method by HPLC




Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?


why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?


what is difference between zero air gas and o2 gas