Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 57553

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 7478

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2617

why using buffers in hplc inteed of water

5 14468

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 3139

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 5528

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 6855

In specificity what parametrs are consider why that parametrs

2 7003

ash or residue in that what will be there.

3 6667

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 3444

What is difference between oos

Gennex,

7 28199

what is the differance between Analytical and semi micro balance?

2 13834

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 11034

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 7325

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 14825

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Un-Answered Questions { Analytical Chemistry }

If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

988

in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

840

how you start the solubility study?

827

if you get peak in blank then what require to do?

974

what is the disso medium for tropsiun chloride

2261

which batch require to use for analytical method validation?

807

WHY pKa value is more important than pH value of the mobile phase in HPLC?

1769

For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

2314

in OSD forms require to use gas chromatography?

834

why does used dry caffien in HPLC calibration?

2032

In which situation we require to prepare the standard solution from sample in Related substance method?

778

How to set analyticl specification for combination products?

747

what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

2630

1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.

2887

What should be the level/ Percentage of Arsenic in Arsenic free zinc.

2233

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