Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 57398

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 7397

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2576

why using buffers in hplc inteed of water

5 14281

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 3083

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 5460

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 6736

In specificity what parametrs are consider why that parametrs

2 6895

ash or residue in that what will be there.

3 6564

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 3365

What is difference between oos

Gennex,

7 27977

what is the differance between Analytical and semi micro balance?

2 13733

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10944

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 7201

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 14675

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Un-Answered Questions { Analytical Chemistry }

identification is for unknown? qualification for known? reporting for LOQ?

685

We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1848

can i use hplc detector to uplc and why?

2250

If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

952

mode of absorption in alimentary canal?

2347

What is the purpose of octyl silane columns?

4256

before starting analytical method valodation what you checking? and how giving preference to start validation?

759

what is the principle involved in turbidometry and nephelometry ?

4123

how we can identify the impurity is coming below loq at transfering site?

825

what is the origin to prepare standard operating procedure

2266

What is delay volume?

1338

What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1569

Why irmoisture balance is used for corrugated box moisture testing

2374

function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

2621

What is the use of tlc and hplc? And when and where use?

1120

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