Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is void volume & dead volueme

Lupin, Bayer,

3 9128

How we will diapose UV (detector) lamp?

Bayer,

1 4440

Principle of single pan analytical balance

Bayer, Amneal Pharmaceuticals, Dr Reddys,

3492




what is the disso medium for tropsiun chloride

809

what is the meaning of linearity,principle of co-relation coefficient?

3 5968

how can we determine RRF value in HPLC FOR CALCULATION OF IMPURITY ?

Macleods,

4 38521

In UV we measure absorbance , how it is happend ? explain me

4 6932

why we are performing residue on ignition?

6 12519




why we are performing residue on ignition?

2 6652

NMR is both qualitative and quantitative?EXPLAIN

2 4109

why buffer is added in solvent system in HPLC ??

Lupin,

10 11173

how can we calculate void volume?give its importance in brief

Natco,

1 6740

What is the function of end capped column?

Cipla,

5 26620

HOW TO CALCULATE THE MASS OF UNKNOWN IMPURITY IN LC-MS? AND WHAT IS THE ROLE OF FRAGMENTATION IN LC-MS ?

1 3925

how calculate column dead volume in hplc ?

Torrent Pharma,

3 16023


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Un-Answered Questions { Analytical Chemistry }

WHY given much noise PDA dector then VWD Dector

587


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

928


For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?

2219


What are modes of quantification in related substances

802


What is Band broading effect explain

477






why does used dry caffien in HPLC calibration?

500


if you have given a blank water how you analyse by general analytical techniques?

627


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.

624


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

5247


Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?

781


why disodium tartarate used in karl-fischer instrument ?.

609


I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

1944


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

226


Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

135


why equlirium conatant of water have 14 value

841