why we are using 6 dosage units in dissolution, and why we
are using 6 tablets in disintegation test.is there any
scientific reason beyond 6?

why we are using 6 dosage units in dissolution, and why we are using 6 tablets in disintegation te..

Answer / madan joshi

The use of six dosage units as the basic sample size in
dissolution is partially due to the configuration of the
dissolution test assembly with six positions. However, in
some statistical procedures such as the estimation of a
confidence interval for precision of a measurement, a
sample size of six represents the point of diminishing
returns where the decrease in the confidence interval from
5 units is significantly greater than the decrease from 6
to 7 units. Thus the added value of obtaining additional
measurements is significantly less once six measurements
have been acquired.

Is This Answer Correct ?    6 Yes 38 No

Post New Answer

More Analytical Chemistry Interview Questions

why the ph scale range is 1 t0 14 and why not beyond 14 and not to below 1?

5 Answers   Orchid, Granules, Avra,

why we need to do karl ficher fector ?

2 Answers   Reliance,

why we are taking 85 ml of concentrated HCl to prepare 1N Solution

4 Answers   SG Phyto Pharma,

who is the father of HPLC?

6 Answers   IPCA, Cipla,

What is the difference between kf  and LOD

5 Answers   Enaltec Labs,

how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,

0 Answers  

How to start the dissolution development for unknown tab?

0 Answers   IPCA,

Which std. used for standrdisation of ZnSO4?

1 Answers  

One pH means how much volts and milivolts?

7 Answers   Dr Reddys,

what is pKa ?

10 Answers   Dr Reddys, Shasun Chemicals,

what is specificity?

4 Answers   Amneal Pharmaceuticals, Aurobindo,

is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

0 Answers   Aarti Drugs,

  • Organic Chemistry Interview Questions Organic Chemistry (289)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (113)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1223)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (300)
  • Chemistry AllOther Interview Questions Chemistry AllOther (77)