why we are using 6 dosage units in dissolution, and why we
are using 6 tablets in disintegation test.is there any
scientific reason beyond 6?




Answer Posted / madan joshi

The use of six dosage units as the basic sample size in
dissolution is partially due to the configuration of the
dissolution test assembly with six positions. However, in
some statistical procedures such as the estimation of a
confidence interval for precision of a measurement, a
sample size of six represents the point of diminishing
returns where the decrease in the confidence interval from
5 units is significantly greater than the decrease from 6
to 7 units. Thus the added value of obtaining additional
measurements is significantly less once six measurements
have been acquired.

Is This Answer Correct ?    6 Yes 38 No






Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

WHAT IS DIFFERENCE B/W MALTINGRANG/DSC

1310


How to choose the which salt is suitable for mobilephase

1867


please explain about aluminium hydroxide assay

67


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1240


In HPLC (Waters) software Empower1,2 &3 what is the updation for each version

1607






Why perchloric acid used for potentiometric titration

1477


Principle of single pan analytical balance

3885


Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?

1267


How to do regeneration of Metacarb Pb plus column?

1412


Tell me something about Vitamin A test method by HPLC

1516


In Assy by potentio metry titration method how select MET U ,DET U, SET U,

362


What is the main difference between ODS1 and ODS2 Hplc column.

2567


what are the standard methods for HPLC?

1649


How we choose the mobile phase for method development.?

20


why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

1094