Follow Our FB Page << CircleMedia.in >> for Daily Laughter. We Post Funny, Viral, Comedy Videos, Memes, Vines...


Is sonication essential in solubility testing of a drug
substance?

Answers were Sorted based on User's Feedback



Is sonication essential in solubility testing of a drug substance?..

Answer / hemant mhaske

FOR THE SOLUBILITY TESTING SONICATION IS NOT REQUIRRED B,COZ WE ARE DETERMINING SOLUBILITY OF COMPOUND IN SUITABLE SOLVENT. MEANS IN WHICH SOLVENT IT IS FREELY SOLUBLE AND IN WHICH SOLVENT LESS SOLUBLE..

Is This Answer Correct ?    11 Yes 0 No

Is sonication essential in solubility testing of a drug substance?..

Answer / pharmainterview

There is no guideline which specifies the sonication
required or not for solubility. So some people prefer to
sonicate and other not. You can't say which one is wright
because you have no evidenced guideline.

Regards
pharmainterviewquestions.blogspot.in

Is This Answer Correct ?    8 Yes 2 No

Is sonication essential in solubility testing of a drug substance?..

Answer / manjeera

sonication is not exactly required for a solubility test of drug substance it is preferable sometimes to check whether it is soluble when it is sonicated.

Is This Answer Correct ?    5 Yes 1 No

Is sonication essential in solubility testing of a drug substance?..

Answer / pradeep reddy

no need to use of sonicate.because substances will freely
soluble in diluent.by hand shake or spinic we can do that
test.

Is This Answer Correct ?    2 Yes 1 No

Is sonication essential in solubility testing of a drug substance?..

Answer / msreddyvelagala

sonication is not mentioned in usp&EP.solubility is checked by handshaking for 1 minute &put it at temperature 20 or 25c for some time.

Is This Answer Correct ?    1 Yes 0 No

Is sonication essential in solubility testing of a drug substance?..

Answer / devendra

There is no need to sonication if it say very soluble, freely soluble, soluble...
In case of practically soluble we can use sonication.

Is This Answer Correct ?    2 Yes 1 No

Post New Answer

More Analytical Chemistry Interview Questions

Please do not join if u got offer in oncotherapies ltd (STRIDESARCOLAB)especially Mr.Mahesh Bhatt team because job is not secure his team and doesn't have confidence on him becareful this offer?

1 Answers   Strides Arcolab,


why 0.02% solution toluene &noHexane using in uv calibration?

1 Answers   Graviti Pharmaceuticals, Orbit Pharma, Ranbaxy, Vimta Labs,


IF WE INCREASE FLOW RATE RT DECRESE.WHY

2 Answers  


In partical size by malven,which parameter is generlly change for development of dry and wet method.

1 Answers  


if out of two set of results of moisture analysis first 1 is passing, second one is failing, is it oos ? or vice a versa first 1 is failing and second one is passing. for information mean value to be reported and in mean value the substance is ppassing, is it oos or normaal mean value to be considered?

1 Answers   JBCPL,






When we calculate Impurity against impurity std.solution and when we calculate impurity against diluted standard with applying RRF?

2 Answers   Torrent Pharma,


What is peak purity and response factor in chromatographic analysis? Why we required to find out response factor?

2 Answers  


I have got selected for Aurobindo Pharma AR&D, HR person is asking me to sign in agreement. can I join?

19 Answers   Aurobindo,


What is the difference in OVI and Residual solvents?

3 Answers   Discovery Intermediates,


As per ICH related substances stability trend limit from initial to shelf life

0 Answers   Medley Pharmaceuticals, Micro Labs,


we can use expired sample for validation and analyst qualification?

0 Answers  


As per OOT for any product what is calculation and how to invetigate the OOT

3 Answers   Aurobindo, Hetero,


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (302)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1385)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)