Answer Posted / hemant mhaske

FOR THE SOLUBILITY TESTING SONICATION IS NOT REQUIRRED B,COZ WE ARE DETERMINING SOLUBILITY OF COMPOUND IN SUITABLE SOLVENT. MEANS IN WHICH SOLVENT IT IS FREELY SOLUBLE AND IN WHICH SOLVENT LESS SOLUBLE..

If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

522

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Why we use potassium dichromate in uv calibration Exact reason behind it??

651

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in gas chromatography what is the difference between gas flow rate and average linear velocity ?

1929

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Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?

2463

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in which situation require to take incident in validation?

731

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Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?

2269

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What is third generation HPLC Columns?

1495

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if you have given a blank water how you analyse by general analytical techniques?

1501

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In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

2592

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In which situation we require to prepare the standard solution from sample in Related substance method?

280

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Which is the highly polar and highly non polar column in HPLC?

1767

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How require to perform linearity as per ANVISA? What are the acceptance criteria?

703

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What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8302

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How to do regeneration of Metacarb Pb plus column?

2071

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what is procedure of actual procedure for registration of drug?

1445

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