Why we are using the methanol in Kf titration?
Answers were Sorted based on User's Feedback
Answer / radheraman singh
Selection of methanol in Kf having following reason.
1 prevent the side reaction between pyridine and SO2.
2 Many compound are soluble in MeOH.
3 MeOH not absorbed moisture and having very less water content.
| Is This Answer Correct ? | 30 Yes | 3 No |
Answer / maulik
to prevent the side reaction of pyridine and so2
| Is This Answer Correct ? | 15 Yes | 2 No |
Answer / g.dasarath
during the titration py.so3 can reacts with h20 which varies
the stoichiometry of H2O and I2 from 1:1 to 2:1, to prevent
such side reactionexcessive anhydrous meoh is added as it
can react with py.so3 which lowers the concentration of py.so3
| Is This Answer Correct ? | 10 Yes | 2 No |
Answer / alexander
the methanol is necessary to carried out the reaction becz the bunchen reaction is occur in presence of lower alcohol and methanol is a lower alcohol(bunchen reaction- basic reaction on which karlfisher is based)
| Is This Answer Correct ? | 0 Yes | 1 No |
Answer / venkataramireddy.bh
ALL PHARMACEUTIAL COMPOUNDS ARE EASILY SOLUBLE IN
METHANOL,THE SELECTION OF METHANOLIS IT SHOULD CONTAIN LESS
WATERCONTENT
from vivimed
| Is This Answer Correct ? | 9 Yes | 12 No |
Answer / natraj kumar
ALL API's ARE SOLUBLE IN METHANOL,LOWEST COST AND WATER
CONTENT IS ALSO LESS.
| Is This Answer Correct ? | 2 Yes | 10 No |
how we can identify the impurity is coming below loq at transfering site?
How do you increase the number of theoretical plates?
why we are using hexane in calibration of number of drop per mL
How can we calculates the solubility of the drug in different medias by injecting in to hplc????(solubility studies)
2 Answers Super Pharmaceuticals,
in what basis wavelength will select for a compound at initial method development trials
Why base line not start from zero in GC Chromatography analysis.
why using Potentometry What Purpose? differance between manual and potentiometry? why using Some of materials in usig potentiometry? What is use of mericuric acetate in Potentiometry
What is the major difference b/w Drift and Noise
4 Answers Aurobindo, Dr Reddys, Reddy Labs,
why hexane is used for FID calibration in GC
In specificity what parametrs are consider why that parametrs
what is the lamp used in SOR?
How can we confirm the HPLC column is end-capped or not? Is it possible to identify by physical appearance?