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How to establish pKa for a new API molecule ?
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HPLC(By using pH Buffer solutions),uv(By using pH Buffer
solutions),Solubility(By using pH Buffer solutions)
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How to prepare 50 ppm ammonia solution form 25% ammonia solution?
What is normality
In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?
What is the optimum period of storage of indicators?
1 Answers Orchid Chemicals and Pharmaceuticals,
What is differences between normality and molarity.in which cases both are used?
importance of internal standard and in what conditions it is used?
if partition coefficient value was positive means, what it indicates ?
What is the acceptance criteria for moisture balance when calibrated with sodium sulfate
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
How you will select column for HPLC development depends on nature of compound and how it will work explain in brief?
why reference flow required during hplc analysis on rid?
what is the defination of accuracy & presicion?
8 Answers Amneal Pharmaceuticals, GSK,
Organic Chemistry 
