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How to establish pKa for a new API molecule ?
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if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?
about method developement in hplc
how require to set assay concentration for standard and sample?
why digestion require in icpms?
what is classification of elemental impurities? what is risk assement in elemental impurities?
Related substance method equivalency on control sample or spiked sample?
how require to interprit the method precision data of hptlc?
We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy
why are measure gas flow " ml " in Gas chromatography
give clarity of linearity and range in method validation
how we can identify the impurity is coming below loq at transfering site?
what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means
What is importance of pH in the Heavy metal test and How it effect on the test results?
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
