How to Perform a Recrystallization ?
Answers were Sorted based on User's Feedback
Answer / taksena gurung
1 First choose a proper solvent to dissolve the impure
substance. the solvent should be like that, in cold
condition the substance is insoluble or partially soluble,
and in hot condition the substance should be completely
soluble.
2 After selecting the suitable solvent, dissolve the given
substance in it, and heat it till the substance completly
dissolve forming clear solution.
3 now filter this hot solution immediatly through the
filter paper. the insoluble impurity remains on the filter
paper and collect the filtrate in a dish and allow to cool
without disturbng the container.
4 the filtrate on cooling gives crystals which are pure,
homogenous, and bigger in size.
Is This Answer Correct ? | 32 Yes | 0 No |
Answer / bhavin mehta
Recrystallization is a laboratory technique used to purify
solids based on their different solubilities.
Recrystallization Steps are
1)Add a small quantity of appropriate solvent to an impure
solid.
2)Apply heat to dissolve the solid.
3)Cool the solution to crystallize the product.
4)Use vacuum fitration to isolate and dry the purified
solid.
Is This Answer Correct ? | 10 Yes | 5 No |
Answer / dinesh gurav
Recrystallisation is a crystallisation process of impure or
crude solid materials in different solvents and at diff.
experimental parameters like temp,pH and quantity of
solvents to elute out the unwanted compounds
[Impurities,Polymorphs] to get a compound of desired
quality.
Is This Answer Correct ? | 4 Yes | 2 No |
Answer / tulasi
if compoune is dissolved in acid
then we have to add base and viceversa
Is This Answer Correct ? | 1 Yes | 9 No |
how pda detector works over uv?
If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?
if tech transfer fails whay require to do?
What is linearity in hplc and how to calibration
principle of UV , PDA , RI detector in HPLC
Why forced degradation studies are performed in hplc method validation?
Which Pharmacopiea follow calibration of HPLC,GC
in loss on drying Why follows on constant weight not more than 0.5 mg, any region
How can we determine Moisture content of HI?
Related substance method equivalency on control sample or spiked sample?
how many types oos and oot
Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?