Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the difference between potentiometry assay and HPLc assay?

Apotex, Torrent Power, Aurobindo, Divis Laboratories,

2 12039

how std. of znso4

1 2765

Which std. used for standrdisation of ZnSO4?

1 1067




In GC and HPLC ,how we can decide which of following method will be suitable or use for quantitation of chromatogram at the time of method development. 1.Area Normalisation 2.External standard method 3.Internal standard method

Atul,

1 4642

In Stability testing if significant change occurs then what will be the action plan?

Cipla,

2 7737

what is mean by profiling of dissolution

1 5443

How decided 10 ppm standard solution in Swab, rinse method.?

1 5875

WHAT IS THE LIQUID PHASE IN DB-624 COLUMN IN GCHS

3 6049




In capadity factor formula is K'= (RT of main compound/RT of first eluted peak)-1 in this formula what is 1

Piramal Healthcare,

1 4729

WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

864

Why we inject a standard 6 times for Related substances by HPLC and 5 times for Assay?

GVK,

3 12652

In HPLC (Waters) software Empower1,2 &3 what is the updation for each version

APL,

1415

hii, i'm had a sample of 1L that gone through extraction & evaporation. i used 0.5ml of methanol for reconstitution before injecting the sample to HPLC. i made a calibration curve using a standard solution but now i'm confused about how to display the concentration i got from the sample. for ex. i got 0.2ug/ml how i'm gonna explane this is for the 1L ? please help .. i'll really appreciate it thanks

1 2264

Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me

Ordain Solutions,

5 5399

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

Micro Labs, VMSRF,

1154


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Un-Answered Questions { Analytical Chemistry }

what is the extinction coefficient for Indomethacin or at 319nm wave length.

2547


Why irmoisture balance is used for corrugated box moisture testing

1059


What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?

2494


Basic principle of ESI?

838


What is the diference between residual solvents and organic volatile matter

684






what type of questions asked on analytical balance and also give answers................all pharma companies?

6101


process of Diclofenac sodium,IP.

877


What are the primary considerations in extractables and Leachables ?

1010


sop of a uv visible spectrophotometer double beam elico model

4159


WHY given much noise PDA dector then VWD Dector

668


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

5335


why we are using benzene, anyline in acetic anhdride assay titration method?

822


In dissolution of tablets/capsules elaborate the Dissolution limit 20.0% to 60% Q in 30 minutes.

729


why we use a particular hplc column for a particular compound give reasons?please

1507


What is Band broading effect explain

565