Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What is the difference between potentiometry assay and HPLc assay?

Aurobindo, Divis Laboratories, Torrent Power, Apotex,

2 12352

how std. of znso4

1 2836

Which std. used for standrdisation of ZnSO4?

1 1153




In GC and HPLC ,how we can decide which of following method will be suitable or use for quantitation of chromatogram at the time of method development. 1.Area Normalisation 2.External standard method 3.Internal standard method

Atul,

1 4786

In Stability testing if significant change occurs then what will be the action plan?

Cipla,

2 7961

what is mean by profiling of dissolution

1 5541

How decided 10 ppm standard solution in Swab, rinse method.?

1 6019

WHAT IS THE LIQUID PHASE IN DB-624 COLUMN IN GCHS

3 6190




In capadity factor formula is K'= (RT of main compound/RT of first eluted peak)-1 in this formula what is 1

Piramal Healthcare,

1 4833

WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

917

Why we inject a standard 6 times for Related substances by HPLC and 5 times for Assay?

GVK,

3 13004

In HPLC (Waters) software Empower1,2 &3 what is the updation for each version

APL,

1483

hii, i'm had a sample of 1L that gone through extraction & evaporation. i used 0.5ml of methanol for reconstitution before injecting the sample to HPLC. i made a calibration curve using a standard solution but now i'm confused about how to display the concentration i got from the sample. for ex. i got 0.2ug/ml how i'm gonna explane this is for the 1L ? please help .. i'll really appreciate it thanks

1 2343

Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me

Ordain Solutions,

5 5547

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

Micro Labs, VMSRF,

1208


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Un-Answered Questions { Analytical Chemistry }

how the compound separate in coulunm,explain

1083


Why to use propyl paraben in HPLC gradient calibration

826


Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?

1518


why octanol used to determine the partition coefficient ?

1029


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

756






how much mass should be there in volumetric flask while in preparation of sample for assay? 

1235


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

1969


In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )

2060


what is partion and column chromatography

1085


how to calibrate hplc & gc

3160


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1077


what is the structure of DOWEX-50

3775


can i use hplc detector to uplc and why?

1007


WHAT IS THE USE OF STARTER ?????????

1138


Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?

1088