Answer / balaji n

Dissolution profile means
collecting samples at different time points while
performing dissolution with respect to the nature and type
of formulation(IR,SR,MR etc).

Dissolution profiling will help you to find the
discreminating power,samness with innovator sample and also
as reference during other investicational studies.

Dissolution profile comparison
1. For accepting product sameness under SUPAC-related
changes.
2. To waive bioequivalence requirements for lower strengths
of a dosage form.
3. To support waivers for other bioequivalence requirements.

Generally for Normal Phase HPLC,stationary phase is Polar.In place of polar if we take non-polar means what happened & why?

7 Answers   Macleods,

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how to hplc calibrated

4 Answers   Dr Reddys, Glochem,

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difference between calibration and validation

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What is the optimum period of storage of indicators?

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what is the method of UV cabinet CALIBRTION

2 Answers  

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why we are using in ph calibrations ph4,7,9.2 buffers only?

5 Answers   Reddy Labs,

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In lcms analysis some times we get sodium and potassium adducts. if the compound is havine sodium ions how can we confirm wether sodium is from sample or it is a adduct?

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What is similarity factor and its use in api strength?

0 Answers  

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what is the d/f b/w normality and molarity and molality..?

1 Answers  

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verification of wave number why you are use in IR calibration

2 Answers  

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IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?

0 Answers   Reddy Labs,

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why 0.02% solution toluene &noHexane using in uv calibration?

1 Answers   Graviti Pharmaceuticals, Orbit Pharma, Ranbaxy, Vimta Labs,

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