Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In burette calibration of Karl fischer Instrument, the multiplication factor 1.00693 is using for how much ml of water dispenced. why

1 1561

how can we decide the limit of cleaning validation? What is the criteria for it?


2 8843

What is difference between Related Substance & Impurity Profile?

Jubilant Organosys,

2 38169

Why we are injecting low load standard conc. while analysing Related Substances by HPLC?

3 6637

why wetlab is called as wetlab

6 10636

In UV-VIS spectrophotometer:My diluent is methanol even though i corrected base line for methanol,In my sample scan i found methanol peak.what is the reason?

2 6582

What is the diffrence between the performing of LOD ordinary drying at voven and vaccum method.


3 5957

How can we calibrate the burette dispencing capacity in metrorm kf titration calibration

1 3969

how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.


in hplc calibration we are using 0.05% acetone why we are using that one and what happen when its conc increases or decreases

Aurobindo, Cadila, Martin,

4 17052

loss on drying we applied vaccum for some compounds and some compounds are at 105c why

3 7515

why we are calibrating autopolarimeter with quartz control plates

1 3513

what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?

Siemens, GHI,


why we use TLC?

8 13361

why disodium tartarate is used for autotitrator calibration

Cipla, Micro Labs,

2 8625

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Un-Answered Questions { Analytical Chemistry }

when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.


in dissolution in one tablets two molecule one is losartan & second is HCTZ losartam is complies in s1 stage & hctz is complies in s2 stage then how to report result losartan s1 stage result or losartan s2 stage result


how to calculate corelation coefficient in G.C Calibration? what is the calculation part?


what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means


some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?


what is %labelled amount in content uniformity of dosage unit and its calculation?


For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?


Can we interpret accuracy from linearity in method validation?


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer


How to start the dissolution development for unknown tab?


give clarity of linearity and range in method validation


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?


Tell me about analytical method validation in QC


what is the extinction coefficient for Indomethacin or at 319nm wave length.