Answer / rajkumar

In columns Stationary phase is Organic phase is coated over
the Silica surface. But during manufacturing it is not
possiable that all active sites(Silica surface)are coated
with organic phase there will be some vacant areas. In that
areas it is possiable to coat with Long chain Organic phase.
so small chain such CH3 is coated in that areas.

Answer / suresh palacharla

A reversed-phase HPLC column that is end-capped has gone
through a secondary bonding step to cover unreacted silanols
on the silica surface.

Answer / ganesh bhavar

for endcapping in reversed phase column use Trimethylamine
means it protect the OH-group silanol group

For Dissolution test why we are Performing 6 Bowls why not more.any were mentioned or in what basis we are performing? --------Veerabhadrarao.M

2 Answers   Lee Pharma, Micro Labs,

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Why KBr is used in FTIR ?

6 Answers  

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Through assay by hplc(anhydrous basis) product got 100.8% .How much the potency of that product.Moisture content is 1.7%,Sulfated ash is 0.02%,Total impurities are 0.3%

2 Answers  

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Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

0 Answers  

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in pentoperazole capsules usp why assay value is substract from dissolution

1 Answers   Ranbaxy,

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0.1 atom gram of the unknown element( X)reacts with 2.4 gram of O2 to produce the oxid product . can you tell us, what is the oxid formula ? a) XO b)X2O3 c)XO2 D) X2O4

1 Answers   Ajanta,

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function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

0 Answers   DRL,

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In specificity what parametrs are consider why that parametrs

2 Answers  

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In HPLC when we use Isocratic method, Gradient method in hplc?

8 Answers   Pharmaceutical,

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what is the difference between isocratic & elution technique?

3 Answers   Laurus,

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What are the different zones in stability according to ICH?

1 Answers   Apotex,

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What is difference between chemical Assay and Hplc assay?

2 Answers   Lee Pharma,

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