What are the concentration limit for class-1 residual solvents in ICH ?



What are the concentration limit for class-1 residual solvents in ICH ?..

Answer / b.gangatharan

1)Benzene(2ppm)
2)1,2-Dichloroethane(5ppm)
3)1,1-Dichloroethene(8ppm)
4)Carbon tetrachloride(4ppm)
5)1,1,1-Trichloroethene(1500ppm)
Ref:ICH Q3C Guidelines
Thanks,
B.Gangatharan,
Caplin Point,Unit-1

Is This Answer Correct ?    3 Yes 2 No

Post New Answer

More Analytical Chemistry Interview Questions

Why void volume(time in seconds) 1 in hplc system suitability

1 Answers  


What is meaning of audit trail in hplc

3 Answers   DRL, Lee Pharma, Raks Pharma,


How we can determine OOT limit in Stability

2 Answers   MSN Pharma,


What is the difference between uplc and hplc

4 Answers   AAU Assam Agricultural University, Hetero,


WHY POTASSIUM HYDROGEN PTHALATE IS USED FOR PERCHLORIC ACID? What is difference btw UV detector & RID detector? what is dissolution? What is unit of KF? what is the significant of pH in HPlc?

1 Answers  






How to decided test concentration in GC analysis.

3 Answers  


Why we use caffeine for HPLC calibration in Detector wave ength accuracy test

60 Answers   Arvind, Aurobindo, Cipla, Reddy Labs, Shasun Chemicals,


why we are using k2cr207 in uv calibration ? why we r not using kmno4?

1 Answers   Glochem, Sidmak Laboratories,


what is the difference between potentiometric titration and karl fischer titration?

0 Answers  


What is the difference between bulk property detectors and Solute property detectors vivimed labs limited

3 Answers  


Which detector is used in uv-vis spectrophotometer?

1 Answers   Glenmark,


what are the basic requirement for the WHO audit?

1 Answers   BioPlus,


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (342)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1387)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)