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What is difference between Chromatographic purity and
Related substances analysis?

Answers were Sorted based on User's Feedback



What is difference between Chromatographic purity and Related substances analysis?..

Answer / arumugam

chromatographic purity is %area normalization is nothing
but Impurity area/Major compound area, applicable for all
known and unknown impurities.

But Related substances is quantification of all impurities
nothing but the impurities are quantified by know
concentration of standard solution.
Impurity (%w/w)= Imp area* Std. Dilution*Potency of Std*RRF
------------------------
Std Area* sample Dilution
RRF= Relative Response factor

Is This Answer Correct ?    27 Yes 1 No

What is difference between Chromatographic purity and Related substances analysis?..

Answer / gayathri

Chromatographic purity is a qualitative analysis and Related substances is a quantitative analysis

Is This Answer Correct ?    6 Yes 5 No

What is difference between Chromatographic purity and Related substances analysis?..

Answer / amol

chrom purtiy is used when all the impurity is known and in
related substances used for both known as well as unknown
impurtiy

Is This Answer Correct ?    8 Yes 21 No

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