Answer / Arti Mourya

Area Normalization Method (ANM) and Diluted Standard Method (DSM) are both used for the determination of trace elements in samples.
1. Area Normalization Method:nIt is used when the sample contains a large matrix that interferes with the analysis of trace elements. In ANM, the area under the peak of the element of interest is divided by the area under the peak of an internal standard to correct for matrix effects.
2. Diluted Standard Method (DSM):nIt is used when the sample contains low concentrations of analytes and a large amount of matrix. In DSM, the sample is diluted with a suitable solvent, and a known concentration of the standard solution is added to the diluted sample.
3. Impurity vs Impurity:nImpurities are unwanted substances present in a pure substance. They can be inorganic or organic compounds that interfere with the analysis or affect the properties of the pure substance.
4. Method Selection:nThe choice between ANM and DSM depends on several factors, including the matrix composition, the concentration of analytes, and the available equipment and standards.

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