Interested to Buy Any Domain ? << Click Here >> for more details...
What is chiral and why this performing in HPLC
- 4 Answers
- 20449 Views
- Hetero, Macleods, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / ashish patel
To control and monitor isomeric impurity (only toxic)
| Is This Answer Correct ? | 14 Yes | 0 No |
Answer / rajasekhar
Some samples have chiral centers . These samples cant saparate reverse phase columns and Narmal phase columns. We can saparate these sample only Chiral columns.Due to charal samples have Isomers, these isomers have same polarity and phisical property.
In chiral columns have one Isomer , which interacts with sample isomers differently , thats why we can saparate.
| Is This Answer Correct ? | 11 Yes | 2 No |
Answer / tejas
attached functional group are different. then it is called chiral. it can be done on GC also or it can be done by reverse phase column also by using pre column derivatization compound.
| Is This Answer Correct ? | 1 Yes | 6 No |
what is the peak purity concept?
5 Answers Graviti Pharmaceuticals, Vimta Labs,
loss on drying we applied vaccum for some compounds and some compounds are at 105c why
What is the purpose of performing dissolution test on routine basis?
what is principal of karl ficher instrument!
what is the difference between IR and FTIR instrument analysis
why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?
1 Answers Cipla, Elder, Vamsi Labs,
difference between quality and quantity
reasons for negative peaks in chromatography
Which is the highly polar and highly non polar column in HPLC?
Why linearity of detector performed in HPLC calibration
What is the deference between Residual solvents and OVI
In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?
Organic Chemistry 
