What is the reason for using the 900ml of dissolution medium

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What is the reason for using the 900ml of dissolution medium..

Answer / kuldeep

bcz we test according to our body condition......and 900 ml is our stomach minimum capicity

Is This Answer Correct ?    19 Yes 29 No

What is the reason for using the 900ml of dissolution medium..

Answer / rahul kulkarni

If one see pharmaceutical reference books it is always
shown dissolution apparatus of 'one' jar only with a
stirrer (paddle/ basket) . So at the beginning of
pharmaceutics pharmacist used a glass jar (beaker) of
capacity 1 lit which is easily available in market.and to
avoid spillage from top they meight have used a little less
volume.(1000-100)=900 ml
Though our full stomach capacity ( of average person) is
approx. 900 ml in actual case after taking Tablet or
capsule we are not drinking 900 ml of water but vary 200
to 500 ml.
The habitual (traditional) 900 ml also refers the diluted
acidic media (0.1 N to 0.01 N) worst condition in stomach
where solubility margins are measured.
When a drug goes into solution the amount in % found
experimentally (ie: by instrumental methods-
Quantification by UV spectrophotometer/ By HPLC) So 900
ml mathematics fits any further dilution when the
readings are in working/ instrumental range

Is This Answer Correct ?    4 Yes 16 No

What is the reason for using the 900ml of dissolution medium..

Answer / janak patel

IN NORMAL HEALTHY VOLUNTEER THE GASTRIC FLUID CONTENT IN
STONMACH IS ABT 900 ML SO..

Is This Answer Correct ?    5 Yes 20 No

What is the reason for using the 900ml of dissolution medium..

Answer / prashant rajpooot

according to the IP.

Is This Answer Correct ?    3 Yes 44 No

What is the reason for using the 900ml of dissolution medium..

Answer / sheetal rajput

According to the IP.

Is This Answer Correct ?    3 Yes 44 No

What is the reason for using the 900ml of dissolution medium..

Answer / ritesh

capacity of basket is 900 ml

Is This Answer Correct ?    3 Yes 52 No

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