Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In dissolution test s1 stage we are getting one bowl 40 % out of 6 bowls what is the root cause you find and how proceed next step? ( Q is 80%)

Reddy Labs,

1 1208

why we inject sample TWICE in ASSAY by HPLC analysis but in RS once?

Aurobindo, Neuland, DRL,

4 6197

What id the resolution factor

1 1967




what is a placebo peak

GMP Pharma, Optimus,

2 2495

what is the effect of injection volume calculate flow rate in perkin elmer headspace? (ccm parameter in HS)

1 831

How can we calculates the solubility of the drug in different medias by injecting in to hplc????(solubility studies)

Super Pharmaceuticals,

2 1998

What is the use of Holmium (III) Oxide???

Finar Chemicals,

1 2842

India is. Under which zone as per QF1.?

Aurobindo, Gland Pharma, Acebright,

4 7170




how to calculate the Step and ripple accuracy for pump gradient test for UPLC?

Wockhardt,

1 3571

why salicylic acid not use for dissolution.

Cipla, Indo Baijin Chemicals,

1 2723

Which water can use Hplc analysis

Dr Reddys, BioGenomics, Reddy Labs,

9 6020

if you have given a blank water how you analyse by general analytical techniques?

653

what is the analytical procedure for COD and BoD

Dai-Ichi,

1 2299

Why pH lies between 0 to 14 only

PI Industries, Unimark Remedies,

4 5984

In chromatograpbic purity 90% is there, in assay 70% is there. How will you prove remaining 30%.

Dr Reddys,

3 4534


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Un-Answered Questions { Analytical Chemistry }

Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc

194


How will u perform degradation study in detectors other thann PDA in HPLC Methodology

1184


How to check hplc detecter sensitivity?

184


What is the difference between BD

701


Why potassium dichromate was using in Uv calibration?

183






Basic principle of ESI?

786


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

5123


how will you do the prep for unstable componds?

619


How we can determine water content in piperazine

843


1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.

1035


what is the disso medium for tropsiun chloride

848


How would you decide dissolution medium for NCE compound of class I drug

664


what is the limit for KF Factor ,we take factor using water we will found factor between 6 to 7 ,while on KF Reagent bottle mentioned 5 mg/ml water content.if we not use dried methanol it is effect on factor.

656


is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

522


Tell me about analytical method validation in QC

1597