In dissolution test s1 stage we are getting one bowl 40 % out of 6 bowls what is the root cause you find and how proceed next step? ( Q is 80%)1 1268
why we inject sample TWICE in ASSAY by HPLC analysis but in RS once?4 6402
What id the resolution factor1 2063
what is the effect of injection volume calculate flow rate in perkin elmer headspace? (ccm parameter in HS)1 894
How can we calculates the solubility of the drug in different medias by injecting in to hplc????(solubility studies)2 2084
In chromatograpbic purity 90% is there, in assay 70% is there. How will you prove remaining 30%.3 4665
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?
why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?
why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?
about method developement in hplc
how to select short coloum and long coloumn for new molecule
How to define samples weight in moisture content
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
How much is the standard area for glc analysis
what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?
Principle of single pan analytical balance
WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE
WHAT IS THE PURPOSE WE USE HCL, CHOPPER, BURNER, MONOCHROMATOR in AAS? PLEASE EXPLAIN BRIEFLY
what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.