How can we calculates the solubility of the drug in different medias by injecting in to hplc????(solubility studies)

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How can we calculates the solubility of the drug in different medias by injecting in to hplc????(sol..

Answer / dhaval shah

One should dissolve fixed quantity of drug in respective media and after filtraion through millipore filter one sghould inject the same quantity into the HPLC injector and from Calibration Curve he/she can definite the identical value of concentration.

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How can we calculates the solubility of the drug in different medias by injecting in to hplc????(sol..

Answer / neeraj sahu

By aqueous solubility profile at different pH.

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