Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

about analytical chemistry



What is differences between normality and which cases both are used?


1 4794

in gas chromatography what is the difference between gas flow rate and average linear velocity ?



what are the ideal conditions for coloumn storage

Claris Lifesciences, Srikem Laboratories,

2 3831

i want to know about headspace and interview question on headspace

Srikem Laboratories,

1 3183

class of solvent regarding Residual solvent e.g. Acetone his class

1 2136

why we multiply 1000 in the determination of kf factor ?

Stellence Pharm Science,

3 4851

why we measure PH of a solution in PH only why not POH ?

Stellence Pharm Science,

1 2449

In Dissolution Test why limit is define Q+5% what is the role of +5%.


Through assay by hplc(anhydrous basis) product got 100.8% .How much the potency of that product.Moisture content is 1.7%,Sulfated ash is 0.02%,Total impurities are 0.3%

2 3672

Why pyrene is also use for calibration if detector

Cipla, Dr Reddys,

1 2229

what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means



In gas chromatographic analysis sometimes we use headspace, why it is required instead of manually injection?

1 2659

How to fix the sample concentration in related substances development.

Novartis, Watson Pharmaceuticals,

3 5232

Who discovered X-ray

Huntsman Corporation,

2 2640

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Un-Answered Questions { Analytical Chemistry }

what type of question will ask in the interview of lab chemist.


why we use a particular hplc column for a particular compound give reasons?please


I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?


what is the purge flow & how to calculate


how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,


Why a1% value is used for some product ? What is the criteria for selection a1% value ?


Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...


why disodium tartarate used in karl-fischer instrument ?.


What is viod volume and peak purity in HPLC?


what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?


Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?


What is intact assay method development.....?


what is the extinction coefficient for Indomethacin or at 319nm wave length.


How we can determine water content in piperazine


what is definition of validation? which components are followed give detail?