Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

which effect is mainly responsible for chromatographic separation when silica is the statinary phase at TLC? thanks in advance

1 3958

what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?

2078

why in GC calibration of linearity regression coefficient should not be less than 0.999

Acacia, Jubilant,

1 6285

why don't we call POH meter? As we all as PH meter

Aurobindo,

4 9414

Why we are having specification 100% above in case of assay as there is only 100% of compound?

MSN Pharma, Nectar Lifesciences,

2 6163

why we are taking 89ml concentrated HCL for preparing 1N HCL

3 9947

Calculate the water content in Di Sodium Tartrate (DST) based on molecular weight?

3 11093

What are the terms used during Melting Range Analysis ?

2 4596

As per USP u/vacuum means (how much vacuum should be applied)?

Mylan,

1 6202

what is difference between zero air gas and o2 gas

IPCA, Vasudha Pharma,

1 10171

While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2901

which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

Hetero,

2213

In which cases factor of KF Reaget got higher side

2 6679

what is the concept for adjustment of pH in HPLC buffer solution ? a. Common ion effect b. Counter ion effect and explain me, how we adapt this principles & what is the role of these principles in our method

Apex, Pentagon Labs,

1 3575

What is the difference between BD

1 3321

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Un-Answered Questions { Analytical Chemistry }

why does used dry caffien in HPLC calibration?

2079

inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

772

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2704

What is aggregate and fragments in SEC?

2157

acceptance criteria for lod & loq by standard deviation of response and slope??

2642

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

888

How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3404

For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1964

For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

2356

How to know the estimated LOQ concentration in ppm

1277

how you fix the limits of impurities?

893

please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1690

Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?

2746

How would you decide dissolution medium for NCE compound of class I drug

2313

iam usig ph buffers merk. manually how to prepare ?

2328

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