Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

Can you please give a suitable definition and an example for understanding the words purity and potency.

Cipla, Reddy Labs, Malladi Drugs and Pharmaceuticals,

6 6007

What is column in chromatography?

Chembond Chemicals,

751

Which Pharmacopiea follow calibration of HPLC,GC

Reddy Labs, Bayer,

3 5770




Why Holium cholorate used in UV Spectro photometer?

Reddy Labs,

7 5689

why we get negative values in uv when i placed sample which has some concetration but not in standard

Nirma,

1 3073

Why water not directed by FID detector 

Amoli Organics, Lupin,

1 3420

what is definition of validation? which components are followed give detail?

843

how the compound separate in coulunm,explain

Wockhardt,

965




What is the principle of HPLC?

Cipla, Lupin,

3 5900

Why methanol & acetonitrile is mostly used for hplc analysis?

DRL,

2 8704

Explain about empower software of analysing?

DRL,

1 3334

why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

Raks Pharma,

881

Why use the Omeprazole as a reference standard to estimate the assay of esomeprazole by HPLC method

Student,

1 2156

are there in uv lamb that is chractrestic for wavelenghth 205 nm ?????

Beni Suef University, Sri Krishna Pharmaceuticals, Graviti Pharmaceuticals,

674

In UV calibration we use Holmium perchlorate solution made in 1.4M perchloric acid The question is that 1.4 M perchloric acid we make is it in water or glacial acetic acid?

4 5828


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Un-Answered Questions { Analytical Chemistry }

How can we determine Moisture content of HI?

1014


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

824


Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

607




996


What is FFA, PV, and PAV value in oil.

501






A ha tc is actual defination of retention time?

178


How to determine water content of bis tetrazole amine mono ammonium salt

1854


What is the purpose of octyl silane columns?

2508


What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

616


why octanol used to determine the partition coefficient ?

920


4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations

1222


wat is the role of michelson interferometer in FTIR and He-Ne lase.detailed answer required in simple language

1026


What is the main difference between ODS1 and ODS2 Hplc column.

1624


What is viod volume and peak purity in HPLC?

1287


In Karl Fischer titration,What is the situation if the material tested is only soluble in water,and not soluble in the common solvents used such as methanol ?? [e.g. Iron III Hydroxide polymaltose]

1442