Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

how can u seperate polar compounds in hplc ?

Meditab, Piramal Healthcare,

1 4642

what is the difference between hplc and uplc?

Mylan, Fresenius Kabi,

5 5114

what is the basis of separation in chromatography?

Anthem,

1 3717




what is the diference between spectroscopy and chromatography

Cipla, PharmChem, Reliance,

2 6931

Why we have to take 42gm of sodium hydroxide instead of 40gm for preparation of 1M Sodium hydroxide as per Pharmacopia? Whether it means the formula for calculating molarity was wrong? 

Ranbaxy, Claris Otsuka,

3 4851

what is internal standard define

Apex, Hikma Pharmaceuticals, IPCA, Coromandel International Limited,

2 1247

pharma industries oriented

Apex, Micro Labs, Zydus Cadila,

786

gc Calibration % RSD failed what is the possible reasons?

Divis Laboratories,

3 5370




What is the procedure for the calibration of ph meter?

IBS,

1 1848

What are the parameters for the method development of Gas Chromatography and GC-HS? 

2 2752

What is the difference between purge septum flow and column flow in gas chromatography?

723

how much mass should be there in volumetric flask while in preparation of sample for assay? 

Reddy Labs,

1105

U have 4 strengths have different coating meterial which one u chose to do forced degradation stady in validation

Reddy Labs,

1 1831

Tell me about analytical method validation in QC

Petronas,

1599

what is procedure of actual procedure for registration of drug?

570


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Un-Answered Questions { Analytical Chemistry }

what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

1137


My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards

150


what is the principle of UV Vis spectroscopy, AAS, ICP OES,ICPAES, ICP-MS and FTIR

5797


Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

183


How to do regeneration of Metacarb Pb plus column?

1216






Why a1% value is used for some product ? What is the criteria for selection a1% value ?

883


What is Band broading effect explain

500


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

824


While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

898


Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

607


What is the principle of Thermal conductivity detector and FID?

1355


USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

504


Can we interpret accuracy from linearity in method validation?

699


how much mass should be there in volumetric flask while in preparation of sample for assay? 

1105


Why Ethanol is Used for Standardization of GC Head space?

2564