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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

how can you determine a compound acidic or basic?

Celon Labs, Cipla,

2 10753

For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)

Reddy Labs,

4 11613

how to develop the shorter run time for pharmacopeial methods having 100 min run time?

Reddy Labs,

3 11141

How you start the method development of unknown compound.

1 5907

How to determine water content of bis tetrazole amine mono ammonium salt

3487

Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard

MSN Pharma,

3 11348

How to use RF and rrf in Rs calculation( either multiply or divide)?

Micro Labs,

4 13822

WHY KBr is used in IR Spectroscopy

GVK,

3 13844

How can you prepare 0.05M Ammonium acetate volumetric solution?

2 25058

Why using 0.5% acetone in methanol mobile phase for HPLC Gradient performance check.

DRL,

2 13635

IF WE INCREASE FLOW RATE RT DECRESE.WHY

2 10640

in hplc calibration injector linearity pass,it means inj and det is good. why to perform detector linearity is it required, if it is required,what is difference between injector and detector linearity in hplc calibration

Dr Reddys, Hetero,

4 15912

how can you decide API molucule acedic or basic compound by test?

Posh Chemicals,

2 10154

acceptance criteria for lod & loq by standard deviation of response and slope??

2592

various methos to calculate precision in validation methods in HPLC?

2 7550


Post New Analytical Chemistry Questions

Un-Answered Questions { Analytical Chemistry }

on saturation solubility study data how we can find out the bcs class of drug?

900


if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

979


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

856


How to calibration of the uv spectroscopy and its test?

1196


If vendor having more imp than monograph then how to proceed? and how to set spec?

935


Many times I don't got a caffeine peak in calibration of hplc using guard column ❓

1820


what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?

10001


we can use expired sample for validation and analyst qualification?

812


In which situation we require to analytical method validation of excipient?

790


in hplc chromatogram started from left to right and in uv spectrum started from left to right

953


about method developement in hplc

1721


how to qualify the impurity?

874


how require to set assay concentration for standard and sample?

923


In Assy by potentio metry titration method how select MET U ,DET U, SET U,

2172


Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?

2729