Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

how can you determine a compound acidic or basic?

Cipla, Celon Labs,

2 7550

For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)

Reddy Labs,

4 7034

how to develop the shorter run time for pharmacopeial methods having 100 min run time?

Reddy Labs,

3 7748




How you start the method development of unknown compound.

1 3578

How to determine water content of bis tetrazole amine mono ammonium salt

2018

Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard

MSN Pharma,

3 7758

How to use RF and rrf in Rs calculation( either multiply or divide)?

Micro Labs,

3 7287

WHY KBr is used in IR Spectroscopy

GVK,

3 10117




How can you prepare 0.05M Ammonium acetate volumetric solution?

2 13728

Why using 0.5% acetone in methanol mobile phase for HPLC Gradient performance check.

DRL,

2 9749

IF WE INCREASE FLOW RATE RT DECRESE.WHY

2 7852

in hplc calibration injector linearity pass,it means inj and det is good. why to perform detector linearity is it required, if it is required,what is difference between injector and detector linearity in hplc calibration

Dr Reddys, Hetero,

4 9393

how can you decide API molucule acedic or basic compound by test?

Posh Chemicals,

2 7078

acceptance criteria for lod & loq by standard deviation of response and slope??

1235

various methos to calculate precision in validation methods in HPLC?

2 4981


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Un-Answered Questions { Analytical Chemistry }

What is the main difference between ODS1 and ODS2 Hplc column.

2049


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

5521


can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

976


HI,I CLEARED BOB CLERK EXAM. MY INTERVIEW WILL BE ON 9TH OCTOBER,2010.PLEASE SEND ME INTERVIEW QUESTIONS AND ANSWERS. THANK YOU.

1049


WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

1432






using gradient pressure in gas chromatography are not ?using gradient pressure why

2167


why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?

1007


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

355


What are modes of quantification in related substances

943


what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?

2349


Why sodium hydroxide used for maintain pH of phosphate buffer

1003


why we should take dst factor for below 1%moisture samples

1467


what is the principle involved in turbidometry and nephelometry ?

2580


Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

334


about method developement in hplc

436