Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

how can you determine a compound acidic or basic?

Celon Labs, Cipla,

2 9658

For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)

Reddy Labs,

4 10073

how to develop the shorter run time for pharmacopeial methods having 100 min run time?

Reddy Labs,

3 9819

How you start the method development of unknown compound.

1 5163

How to determine water content of bis tetrazole amine mono ammonium salt

2954

Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard

MSN Pharma,

3 10050

How to use RF and rrf in Rs calculation( either multiply or divide)?

Micro Labs,

4 12016

WHY KBr is used in IR Spectroscopy

GVK,

3 12363

How can you prepare 0.05M Ammonium acetate volumetric solution?

2 22393

Why using 0.5% acetone in methanol mobile phase for HPLC Gradient performance check.

DRL,

2 12088

IF WE INCREASE FLOW RATE RT DECRESE.WHY

2 9646

in hplc calibration injector linearity pass,it means inj and det is good. why to perform detector linearity is it required, if it is required,what is difference between injector and detector linearity in hplc calibration

Dr Reddys, Hetero,

4 13902

how can you decide API molucule acedic or basic compound by test?

Posh Chemicals,

2 9038

acceptance criteria for lod & loq by standard deviation of response and slope??

2076

various methos to calculate precision in validation methods in HPLC?

2 6565


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Un-Answered Questions { Analytical Chemistry }

How to calibration of the uv spectroscopy and its test?

655


What is the difference between purge septum flow and column flow in gas chromatography?

1819


How much is the standard area for glc analysis

1735


What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio

1327


if tech transfer fails whay require to do?

320






What is importance of pH in the Heavy metal test and How it effect on the test results?

1736


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

1747


how many types of balance calibration test?

1702


from where i get mortar pastle for glass bottle crush? it's required for testing of it?

1725


how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,

2030


What is split ratio in Gc? Splitless? how requirr to select?

315


If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

1741


What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

298


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

343


how to get accurate result for Residue on evaporation in purified water

1106