Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

WHICH PRESSURE IS HIGH EITHER INJECTOR OR DETECTOR IN GAS CHROMATOGRAPHY

Avon Organics, Dr Reddys, Reddy Labs,

4 11169

What is the procedure for UV-spectrophotometer calibration?

6 62905

What should be the calibration procedure for wavelength accuracy in case of HPLC?

4 15994

How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

NCL,

3405

How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?

NCL,

3914

How can we Qualify a unknown impurity by HPLC

3 13367

full name of OOS & OOT ? Dercribe it with details ? why this is needed in pharma industry ?

Orchid,

10 39096

why KBr is used in FTIR SPECTROSCOPY and why is it necessary to triturate KBr during FTIR analysis?

Hikal, Lupin, Wockhardt,

25 124743

what is stability study ? why it is needed and how itis done

Dr Reddys, RB,

2 29246

why water, methanol, ethanol ets solvents are used in UV SPECTRIPHOTOMETER for blank reading ?

7 29039

why the same column give different retention time in hplc?

7 17239

How will decide to use HPLC OR GC for developing method for unkown compund

5 16842

What is the major difference b/w Drift and Noise

Aurobindo, Dr Reddys, Reddy Labs,

4 39889

what king of work is done in Regulatory Affairs in Pharma industry ?

Quintiles,

3 15057

can some other acids like nitric acid or HCl can be used in the calibration of UV.Vis. spectrophotometer????

Cipla,

2 10191

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Un-Answered Questions { Analytical Chemistry }

How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

4371

How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2440

While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2902

what is the difference between potentiometric titration and karl fischer titration?

3260

please explain about aluminium hydroxide assay

1187

effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?

1005

Why Ethanol is Used for Standardization of GC Head space?

4273

What is the purpose of octyl silane columns?

4340

AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?

2114

if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

1049

Why sodium hydroxide used for maintain pH of phosphate buffer

2486

is it nessesary to do solution stability for 7 days?

821

if you given one product then which tests you will perform?

750

if instrument calibration fails then what require to do?

1020

what you do when compound having dwel wavelength?

808

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