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how decide the clining method and cleaning method validation require for this perticular products?


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More Analytical Chemistry Interview Questions

hii, i'm had a sample of 1L that gone through extraction & evaporation. i used 0.5ml of methanol for reconstitution before injecting the sample to HPLC. i made a calibration curve using a standard solution but now i'm confused about how to display the concentration i got from the sample. for ex. i got 0.2ug/ml how i'm gonna explane this is for the 1L ? please help .. i'll really appreciate it thanks

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why we use x terra columns at higher ph ?

2 Answers   Hetero,


perchloric acid&glacal acetic acid both are acids but reaction is complete in volumetric titrations.how?

1 Answers  


In UV calibration we use Holmium perchlorate solution made in 1.4M perchloric acid The question is that 1.4 M perchloric acid we make is it in water or glacial acetic acid?

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According to ICH,India is coming under which climatic zones?

1 Answers   Cipla,


in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

0 Answers  


what is the use of tap density apparatus? why we calculate it? what is the difference between the bulk density and tap density?

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what is reverse phase chromarography&normal phase chromatography

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What is the difference between HPLC and GC?

3 Answers  


if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

0 Answers  


What is the b/W dead volume and dwell volume ?

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Dear sir, This is R.Kadambavadani working in a pharma industry. while doing RS analysis of ibuprofen API, unknown peak eluting some times in the 0.6 Min RT. Kindly send me what is the exact reason behind that. also am using ACN the mobile phase.

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