Answer / dm

prepare the standard solution as per impurity level.

Answer / yantesh varshney

If Impurity peak have very low response in this case we prepare diluted standard as per criteria generally at 1 % level to check and compare the impurity with in limit .

Answer / sunil

Actually it is based on the impurity level if any impurity does not meet his LOQ level at that concentration w.r.t the API in that case we need to increase concentration of the API and if the peak is normal no need to prepare diluted std but if peak goes saturation in that case need to inject diluted std at SHI level

How to calculate %w/w and %v/v of a component(or solvent)by NMR

1 Answers   ACME, Vimta Labs,

---

analytical method validation require to with respect to release specification or shelf life specification?

0 Answers  

---

Why we are performing wavelength accuracy at lower and higher wavelengths in HPLC calibration

3 Answers  

---

How to decide the standard concentration for related substances hplc method

1 Answers  

---

what is difference between zero air gas and o2 gas

1 Answers   IPCA, Vasudha Pharma,

---

in determination of(acetone) moister content we are using methanol replaced by pyredine.what hapend in that reaction.

2 Answers   Glenmark, Neuland,

---

Wath is the differenc between two column HPLC wich have the samme support , lenth , pore size, etc.. But different name .for exemple : Spherisorb / lichrosorb

2 Answers   NDA,

---

Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?

0 Answers  

---

how require to calculate mass balance in related sub?

1 Answers  

---

what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

0 Answers   Graviti Pharmaceuticals,

---

What is difference btw UV detector & RID detector

4 Answers  

---

Calculate the water content in Di Sodium Tartrate (DST) based on molecular weight?

3 Answers  

---