why inject diluted standard solution in related substance
analysis by HPLC?
Answers were Sorted based on User's Feedback
Answer / dm
prepare the standard solution as per impurity level.
Is This Answer Correct ? | 21 Yes | 6 No |
Answer / yantesh varshney
If Impurity peak have very low response in this case we prepare diluted standard as per criteria generally at 1 % level to check and compare the impurity with in limit .
Is This Answer Correct ? | 6 Yes | 0 No |
Answer / sunil
Actually it is based on the impurity level if any impurity does not meet his LOQ level at that concentration w.r.t the API in that case we need to increase concentration of the API and if the peak is normal no need to prepare diluted std but if peak goes saturation in that case need to inject diluted std at SHI level
Is This Answer Correct ? | 1 Yes | 0 No |
why we use vanillin in melting range calibration
What are the primary standards?
what is use in calibration of conductivitimeter?
1 Answers Claris Lifesciences, SRF,
why deutiriated chloroform used in NMR for sample prepration. what reaction takes place.give reasons
how the compound separate in coulunm,explain
why hydrogen and zero air used for flame ignition in gc?
how can delete the impurity in 1-(2:6 dichloro phenyl)-2-indolenone.and desolving the impurity in which solvent but does not desolve product in solvent.
Why we have to use KBr pellet technology ?
How to establish relative response factor for hplc. Why it is required?
why are not used methonol in kf titrator to find out water content in ketones?
how calculate column dead volume in hplc ?
What is the Column Endcaping in HPLC ?