why octanol used to determine the partition coefficient ?



why octanol used to determine the partition coefficient ? ..

Answer / Rohit Kumar Bhadani

Octanol is commonly used as a solvent in the determination of the partition coefficient (log P) because it mimics the hydrophobic properties of biological membranes. It allows for the comparison of a compound's distribution between an organic phase and water, providing insights into the substance's potential bioavailability and toxicity.

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