In lcms analysis some times we get sodium and potassium
adducts. if the compound is havine sodium ions how can we
confirm wether sodium is from sample or it is a adduct?

Answers were Sorted based on User's Feedback



In lcms analysis some times we get sodium and potassium adducts. if the compound is havine sodium ..

Answer / sri krishna

for sodium contamination adduct the intensity of the peak is
very low when compared to the sample sodium peak

Is This Answer Correct ?    3 Yes 2 No

In lcms analysis some times we get sodium and potassium adducts. if the compound is havine sodium ..

Answer / spgoswami

If the precursor is sodium ion then intense peak will be of
sodium only rather than the same adduct so we can conclude
by observing lc-ms /TIC chromtgram
Regards

Is This Answer Correct ?    0 Yes 1 No

Post New Answer

More Analytical Chemistry Interview Questions

Why we compare unequal concentrated solutions in heavy metals test. For example comparing the test solution with 1 ppm lead standard and telling it's less than 20ppm?

1 Answers   Micro Labs, Mistair,


Loss of linearity in tkn analysis, possible reasons?

0 Answers  


How we can perform Linearity study for validation by HPLC with very low conc of sample

1 Answers  


on saturation solubility study data how we can find out the bcs class of drug?

0 Answers  


in dissolution in one tablets two molecule one is losartan & second is HCTZ losartam is complies in s1 stage & hctz is complies in s2 stage then how to report result losartan s1 stage result or losartan s2 stage result

1 Answers   Dishman,






What is difference b/t uv detector and rid

5 Answers  


what is rt and rrt? how we find rrt? relation between rt and rrt/

1 Answers   Cadila,


why phenolpthalin gives pink colour when we titrate aganist sodium hydroxcide & phenolpthalin gives colourless titrate aganist hydrochlric acid which is un burate

1 Answers  


how can you decide API molucule acedic or basic compound by test?

2 Answers   Posh Chemicals,


why results are variation in same samples analysis in gc and hplc ?

2 Answers  


why the same column give different retention time in hplc?

7 Answers  


if rsd failed then what require to do?

0 Answers  


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (342)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1387)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)